PP058 - EARLY NUTRITIONAL ADEQUACY AND CLINICAL OUTCOMES IN CRITICALLY ILL PATIENTS: A SINGLE-CENTER OBSERVATIONAL STUDY
PP058
EARLY NUTRITIONAL ADEQUACY AND CLINICAL OUTCOMES IN CRITICALLY ILL PATIENTS: A SINGLE-CENTER OBSERVATIONAL STUDY
J. G. Lee2, J. Y. Jeong1,*, S. M. Baik2, H. J. Shim2, Y. J. Im3
1Clinical Nutrition, 2Surgery, 3Nursing, Ewha Womans University Mokdong Hospital, Seoul, Korea, Republic Of
Rationale: Adequate nutritional support is an essential component of critical care; however, the optimal amount of energy and protein delivery during the early phase of critical illness remains controversial. This study aimed to evaluate the adequacy of early nutritional support in critically ill patients and its association with clinical outcomes.
Methods: This observational study included adult patients admitted to a single-center intensive care unit (ICU). Patients who received exclusive enteral and/or parenteral nutrition for at least 3 days after ICU admission were included, while those with oral intake or ICU readmission were excluded.
Calorie requirements were defined as 20 kcal/kg/day, and protein requirements were standardized at 1.2 g/kg/day. Nutritional adequacy was calculated as the ratio of delivered to required intake. Nutritional data were prospectively collected, and baseline clinical variables were obtained retrospectively. The primary outcome was hospital mortality.
Results: A total of 55 patients were analyzed, with a hospital mortality rate of 18.2%. The mean APACHE II and mNUTRIC scores were 26.5±8.6 and 4.9±1.6, respectively. Non-survivors received significantly higher calorie intake on day 1 compared to survivors (442 vs. 237 kcal, p=0.025). This pattern persisted during the first 7 days, although differences were not statistically significant at later time points. Three-day and seven-day cumulative calorie and protein delivery were higher in non-survivors, but no significant associations with mortality were observed. In multivariate analysis, early nutritional adequacy was not independently associated with mortality after adjustment for illness severity.
Conclusion: Higher early calorie delivery, particularly on the first day of ICU admission, was associated with increased mortality, although this association was attenuated after adjustment for severity.
Disclosure of Interest: None declared