P418 - ASSOCIATION BETWEEN NUTRITIONAL STATUS, ENERGY-PROTEIN-MICRONUTRIENT INTAKE, AND MORTALITY IN CRITICALLY ILL PATIENTS RECEIVING ENTERAL TUBE FEEDING

P418

ASSOCIATION BETWEEN NUTRITIONAL STATUS, ENERGY-PROTEIN-MICRONUTRIENT INTAKE, AND MORTALITY IN CRITICALLY ILL PATIENTS RECEIVING ENTERAL TUBE FEEDING

N. T. Ozer¹, S. Onuk², S. Temel³, R. C. yuksel³, M. Sungur³, K. Gundogan^3,*

¹Nutrition and Dietetics, Agri Ibrahim Cecen University, Agri, ²Division of Intensive Care Unit,, Kayseri Training and Research Hospital, ³Division of Intensive Care Unit, Department of Internal Medicine, Erciyes University, Kayseri, Türkiye

Rationale: Malnutrition is a pervasive problem in the intensive care unit(ICU), if unaddressed with sufficient nutritional support, can result in worsened clinical outcomes. The objective of this study was to investigate the relationship between energy, protein and micronutrient intake and mortality in malnourished and well-nourished critically ill patients.

Methods: The cohort study was retrospectively conducted in a medical ICU. Patients who had been admitted within the first 48 hours were categorised as either well-nourished (mNUTRIC score:0-4) or malnourished (mNUTRIC score:5-9). The daily energy, protein, and micronutrient intake levels of patients receiving enteral tube feeding were meticulously monitored over the initial seven-day ICU day.

Results: A total of 226 patients were included in the study ( Malnourished= 137 pts, well-nourished=89 pts). The median age of the study sample was 65.0(47.8-74.0) years. Patients with malnutrition exhibited a lower energy adequacy percentage compared to those who were well-nourished (median: 52.3% vs. 68.3%, p=0.001). Malnourished patients exhibited significantly lower intake of chromium, copper, iodine, iron, manganese, molybdenum, selenium, biotin, vitamins A and C, and D compared to well-nourished patients (p<0.05 for all). Multivariate Cox regression analysis revealed that the mNUTRIC score was a significant predictor of ICU mortality (HR(95%CI): 1.235(1.112-1.371), p<0.001). Kaplan-Meier analysis demonstrated that malnourished patients exhibited a significantly lower survival probability in comparison to well-nourished patients (median(95%CI):29.0(16.2-41.8) vs. 17.0(15.0-19.0) days, p=0.001)(Figure 1).

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Conclusion: Critically ill adult patients with malnutrition exhibited significantly lower levels of energy and certain micronutrients intake via the enteral tube feeding, and a lower probability of ICU survival.

Disclosure of Interest: None declared