P099 - PREVALENCE OF METABOLIC SYNDROME AND ASSOCIATED COMPLICATIONS IN POST-RENAL TRANSPLANT PATIENTS: A SINGLE-CENTER OBSERVATIONAL STUDY

P099

PREVALENCE OF METABOLIC SYNDROME AND ASSOCIATED COMPLICATIONS IN POST-RENAL TRANSPLANT PATIENTS: A SINGLE-CENTER OBSERVATIONAL STUDY

S. Sahoo^1,*, M. Mohapatra¹, B. Bhoi¹, N. Mohanty²

¹Dietetics, ²Nephrology Department, Apollo Hospitals, Bhubaneswar, India

Rationale: Renal transplantation is the preferred therapeutic option for patients with ESRD. This study aims to assess the prevalence of metabolic syndrome and associated clinical parameters in post-renal transplant recipients attending a tertiary care center.

Methods: A total of 154 adult renal transplant recipients were enrolled in this prospective observational study . Anthropometrics data of patients undergone kidney transplant were recorded at the time of transplant, and  they were asked to come to diet OPD on quarterly  for follow up, parameters like Bp, FBS,TG ,weight changes, RFT were recorded and analyzed. All patients were counseled regarding transplant diet as per their blood parameters

Results: Among the 154 participants (mean age: 37.4 ± 5.1 years), 82% were male and 18% female. the mean BMI was 28.6 ± 4.3 kg/m² in males and 23.9 ± 3.7 kg/m² in females. The average body weight increased from 61.2 ± 6.9 kg at baseline to 67.5 ± 5.2 kg at 12 months post-transplant (p < 0.001).40.3% developed post-transplant diabetes (FBS ≥ 126 mg/dL), with a mean FBS of 143.6 ± 19.2 mg/dL and mean BMI of 27.4 ± 2.9 kg/m². 49.3% had TG ≥ 150 mg/dL, with a mean TG level of 188.3 ± 47.8 mg/dL and mean BMI of 28.1 ± 3.1 kg/m².30.5% had elevated BP (≥130/90 mmHg). 75.3% of participants followed the dietitian’s advice, while 24.7% were non-adherent. Those non-adherent had significantly higher levels of FBS and TG (p < 0.05).5.8% experienced graft dysfunction requiring readmission due to abnormal RFTs.10.4% reported issues such as urinary tract infections, constipation, seizures, and hearing loss. 3 patients (1.9%) declared during the follow-up period.

Conclusion: Transplant patients were at increased risk of weight gain along with Metabolic syndrome and associated complications.More elaborated study needed to create awareness among transplant patients to control such complications.

Disclosure of Interest: None declared