P137 - COMPARISON OF PARENTERAL NUTRITION COMPOSITION IN PATIENTS WITH ABDOMINAL CATASTROPHE: THE IMPACT OF MACRONUTRIENT DISTRIBUTION AND TOTAL ENERGY INTAKE ON HEALING

P137

COMPARISON OF PARENTERAL NUTRITION COMPOSITION IN PATIENTS WITH ABDOMINAL CATASTROPHE: THE IMPACT OF MACRONUTRIENT DISTRIBUTION AND TOTAL ENERGY INTAKE ON HEALING

T. Olejár^1,*, K. Kisova¹, J. Visek¹, V. Blaha¹

¹FN HK, Hradec Kralove, Czech Republic

Rationale: Parenteral nutrition is essential in managing patients with abdominal catastrophe when enteral feeding is not possible. The optimal balance of macronutrients may influence not only metabolic stability but also the healing process. This study aimed to evaluate the impact of PN composition on healing outcomes.

Methods: Patients were divided into two groups based on healing status: healed (n = 19) and non-healed (n = 3). Healing was defined as closed fistula and no open abdomen. For each patient, average daily intake of carbohydrates, amino acids, lipids, and total energy from parenteral nutrition was recorded. Differences between groups were analyzed using the non-parametric Mann-Whitney U test that was used due to the limited size of the non-healed group.

Results: Healed patients received a slightly lower average intake of carbohydrates (281.05 g vs. 300 g) and energy (1695.2 kcal vs. 1957.3 kcal) than non-healed patients. Conversely, the intake of amino acids (115.2 g vs. 105.2 g) and lipids (30 g vs. 19.5 g) was higher in te non-healed group. However, none of these differences were statistically significant (Carbohydrates: p = 0.17; Amino acids: p = 0.185; Lipids: p = 0.389; Energy: p ≈ 0.186).

Conclusion: Although trends were observed in macronutrient distribution and energy intake between healed and non-healed patients, statistical analysis did not confirm significant differences. Further research with larger patient samples is needed to better define the role of parenteral nutrition composition in healing.

Disclosure of Interest: None declared