PD1036 - THE IMPACT OF A REMOTE MULTIMODAL PREHABILITATION PROGRAMME ON NUTRITIONAL RISK IN CANCER PATIENTS: A RETROSPECTIVE ANALYSIS

PD1036

THE IMPACT OF A REMOTE MULTIMODAL PREHABILITATION PROGRAMME ON NUTRITIONAL RISK IN CANCER PATIENTS: A RETROSPECTIVE ANALYSIS

N. Cruz^1,2,*, N. Tetlow¹, T. Boucher¹, A. Beebeejaun¹, J. Lipman¹, A. Dayanamby¹, J. Whittle^1,3

¹Department of Targeted Intervention, Centre for Perioperative Medicine, Human Physiology and Performance Laboratory (HPPL), University College London Hospitals, ²Integrated Hospital Care Institute, Cleveland Clinic London, ³Department of Anaesthesia and Perioperative Medicine, University College London Hospitals, London, United Kingdom

Rationale: Preoperative malnutrition drives adverse surgical outcomes. Prehabilitation optimises preoperative physiological reserve. The PG-SGA is the gold standard for nutritional screening in oncology(1,2). This retrospective analysis evaluated a remote multimodal prehabilitation program's impact on PG-SGA scores, functional capacity, and postoperative outcomes in patients undergoing major surgery for cancer at UCLH.

Methods: 295 patients receiving major oncological surgery after prehabilitation were included (Urology n=129; UGI n=86; Gynaecology n=49; LGI n=31) from 2022 to 2025. PG-SGA and Sit-to-Stand (STS) scores were compared at baseline (T0) and pre-operative (T1). Outcomes included Clavien-Dindo (CD) and hospital length of stay (LOS).

Results: PG-SGA(p <0.001) and STS(p< 0.001) improved significantly. UGI (Mean:2.06±3.36) and Gynaecology (Mean:2.08±3.33) showed the greatest nutritional improvement. 70.6% reduction in critical nutrition risk (PG-SGA ≥9) was observed, decreasing from 17 to 5. Major postoperative complications (CD≥3) were low (n=13), but preoperative PG-SGA correlated with severity (Spearman’s rho=0.13, p=0.048, n=232). A positive trend was observed between PG-SGA scores and hospital LOS(p=0.062).

Image:

Conclusion: PG-SGA is a sensitive tool for monitoring perioperative nutritional optimization. Remote multimodal prehabilitation rescues patients at high nutritional risk. Given its correlation with complication severity, nutritional optimization should be integrated into oncological surgical pathways.

References:         1.  Duarte-Afonso J, et al. Prehabilitation in Surgery: Pre-conditioning the Patient for Major Procedures. Surgical Clinics of North America.2026;106(1). 

        2.  Ying L, et al. Predictive value of the Scored Patient-Generated Subjective Global Assessment (PG-SGA) for postoperative complications in patients with gastric cancer. BMC Gastroenterology.2022;22(1):418.

Disclosure of Interest: None declared