P962 - THE EFFECT OF SMOKING CESSATION INTERVENTIONS ON LDL LEVELS IN PATIENTS WITH ISCHEMIC STROKE

P962

THE EFFECT OF SMOKING CESSATION INTERVENTIONS ON LDL LEVELS IN PATIENTS WITH ISCHEMIC STROKE

M.-Y. Wu^1,*

¹Nursing Department, National Taiwan University Hospital Yun¬Lin Branch, Dou Liu City, Taiwan, Province of China

Rationale: A cardiac study indicates that smoking significantly increases the risk of stroke, with the risk being positively correlated with the amount of smoking. Smoking raises total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C), and elevated levels of either total cholesterol or LDL-C are associated with an increased risk of stroke.

Methods: From 2021 to 2023, for patients experiencing their first ischemic stroke who were smokers, regular outpatient follow-ups and hyperlipidemia treatments were provided. Within 30 days after stroke onset, smoking cessation education was delivered either during hospitalization or outpatient visits, and patients were followed up for one year. Paired sample t-tests were conducted to analyze the impact of smoking cessation education interventions on LDL levels before and after the intervention in both the successful cessation group and the unsuccessful cessation group.

Results: A total of 58 individuals completed a one-year follow-up, with an average smoking history of 38.7 years and an average of 19 cigarettes smoked per day. The study tracked changes in LDL-C levels over one year before and after smoking cessation education. In the group that successfully quit smoking, the average LDL-C level decreased by 23.6 mg/dL (p < 0.000); in the group that failed to quit smoking, the average LDL-C level decreased by 31 mg/dL (p < 0.001). The results suggest that, under regular lipid-lowering medication treatment, smoking cessation intervention—regardless of its success—can benefit lipid control in patients with ischemic stroke.

Conclusion: In patients with ischemic stroke and dyslipidemia, in addition to medication treatment, non-pharmacological lifestyle changes are equally important. These changes can help alleviate the discomfort associated with smoking cessation and improve lipid control, thereby reducing the risk of recurrent cardiovascular events.

Disclosure of Interest: None declared