PP034 - ASSOCIATIONS BETWEEN ULTRA-PROCESSED FOOD ADDICTION (UPFA), INFLAMMATION AND MICRONUTRIENT STATUS IN EATING DISORDERS
PP034
ASSOCIATIONS BETWEEN ULTRA-PROCESSED FOOD ADDICTION (UPFA), INFLAMMATION AND MICRONUTRIENT STATUS IN EATING DISORDERS
A. Seelarbokus1,*, M. Fatseas1,2,3, D. Sanchez2, L. Marinelli2, S. Berthoz1,4
1Institute for Cognitive and Integrative Neuroscience (INCIA), University of Bordeaux , 2CHU Bordeaux, 3CH Charles Perrens, Bordeaux, 4Institut Médico-chirurgical Montsouris, Paris, France
Rationale: Increasing evidence suggests a very high prevalence of UPFA in people with eating disorders (EDs). Yet, associations between UPFA, inflammatory and micronutrient status in ED populations are understudied. We aimed to determine (1) UPFA prevalence and severity in treatment seeking people with EDs; associations between UPFA symptoms count and diagnosis severity and (2) depression, anxiety, and intake of NOVA4 food items; (3) their associations with inflammatory and micronutrient levels.
Methods: Using data from 267 patients who completed the modified Yale Food Addiction Scale (mYFAS2.0) and the Hospital Anxiety Depression Scale, non-parametric tests were used to explore associations between UPFA diagnosis and symptoms count, NOVA4 foods consumption and CRP and micronutrient concentrations.
Results: UPFA diagnosis’ overall prevalence was 76.0%, 64.0% in restrictive anorexia nervosa (AN), 82.5% in binge-purging AN, 100% in Binge Eating Disorder and Bulimia Nervosa, and 60.0% in Other Specified Eating Disorders. UPFA scores correlated with anxiety (symptoms count and diagnosis severity: both rho=0.167, p=0.007), depression (symptoms count: rho=0.154, p=0.01; severity: rho=0.142, p=0.02). Across all ED subtypes those with an UPFA diagnosis had higher NOVA4 foods consumption (all p<0.001). Correlations were noted between CRP and UPFA diagnosis severity (rho=0.155; p=0.04), between UPFA diagnosis severity, vitamin B12 (rho=-0.189; p=0.01) and ferritin (rho=-0.155; p=0.03), UPFA symptoms count and vitamin B12 (rho=-0.170; p=0.02) and ferritin (rho= -0.155; p=0.03).
Conclusion: We confirm the high prevalence of UPFA in EDs and highlight its impact on the inflammatory and micronutrient status of the patients. Our findings warrant to consider UPFA as part of the integrative nutritional and mental health treatment of people with EDs.
Disclosure of Interest: None declared