PD692 - ADAPTED NUTRIPAL SCREENING AND OVERALL SURVIVAL IN CANCER PATIENTS IN PALLIATIVE CARE

PD692

ADAPTED NUTRIPAL SCREENING AND OVERALL SURVIVAL IN CANCER PATIENTS IN PALLIATIVE CARE

M. D. P. Rodrigues¹, A. D. V. Firmino¹, T. M. Miola^1,*

¹Nutrition, ACCamargo Cancer Center, São Paulo, Brazil

Rationale: Nutritional risk is common in cancer patients receiving palliative care. The Nutripal screening tool was developed in Brazil for this group of cancer patients and integrates the Patient-Generated Subjective Global Assessment (PG-SGA) and the Glasgow Prognostic Score (GPS).

Methods: This retrospective study included cancer patients in palliative care, hospitalized between July 2023 and July 2024. The Nutripal screening was applied in its original version (grades 1 to 4), in which patients with a score ≥ 9 on the SGA-PPP scale were evaluated for inflammatory response using C-Reactive Protein (CRP) and albumin, and in an adapted version (grades 1 to 3), considering only CRP. The primary outcome was overall survival (OS) at 180 days, defined as the interval (in days) between the date of application of the SGA-PPP and death.

Results: Two hundred patients were included, of whom 79% had a score ≥ 9 points on the ASG-PPP scale and 76% were diagnosed with severe malnutrition. In the application of the Nutripal screening, in both versions, a statistically significant difference was observed between the groups in the Cox regression (p = 0.001). In the original version, patients classified in nutritional risk grade 4 had significantly lower overall survival (OS) compared to the other grades (p = 0.02; HR = 1.57; 95% CI: 1.04–2.36). Similar results were observed in the adapted version, with higher mortality in nutritional risk grade 3 (p = 0.02; HR = 1.57; 95% CI: 1.04–2.36).

Conclusion: Our study proposed an adapted version of the Nutripal screening tool, without the use of albumin, expanding its potential in clinical practice. The adapted tool demonstrated good applicability in clinical practice and was associated with worse overall survival (OS) in patients classified in the highest degree of nutritional risk.

Disclosure of Interest: None declared