PD386 - APPLICATION OF THE GLOBAL LEADERSHIP INITIATIVE ON MALNUTRITION (GLIM) CRITERION FOR THE DIAGNOSIS OF MALNUTRITION IN PATIENTS WITH CHRONIC KIDNEY DISEASE: A SCOPING REVIEW
PD386
APPLICATION OF THE GLOBAL LEADERSHIP INITIATIVE ON MALNUTRITION (GLIM) CRITERION FOR THE DIAGNOSIS OF MALNUTRITION IN PATIENTS WITH CHRONIC KIDNEY DISEASE: A SCOPING REVIEW
N. T. Bellafronte1,*, P. Medeiros 1, C. P. Freire 2, E. I. Rabito 1, N. T. Bellafronte1
1Nutrition, Federal University of Paraná, 2Nutrition, Hospital Santa Casa de Misericórdia, Curitiba, Brazil
Rationale: The lack of standardized criteria for malnutrition diagnoses led to the development of the Global Leadership Initiative on Malnutrition (GLIM) in 2018, increasingly applied in chronic kidney disease (CKD), a population at high-risk for disease-related malnutrition. This review maps the GLIM operationalization in CKD.
Methods: A scoping review was developed following the Joanna Briggs Institute methodology. Searches were conducted up to November 20, 2025, in PubMed, Embase, Scopus, Web of Science, and CINAHL databases, using terms related to CKD (≥ 18 years old; population), GLIM (concept) and malnutrition (context). Data were extracted and synthesized.
Results: Of 364 records, 27 studies were included (observational study design: 70%, n=19), with 44% of them (n=12) assessing patients aged ≥ 60 y, 41% of studies (n=11) conducted in patients on dialysis, comprising 49,161 individuals. Pré-GLIM malnutrition screening was reported in 41% (n=12) of reports, mainly by Nutritional Risk Screening 2002 (50%, n=6), Malnutrition Universal Screening Tool or Mini-Nutritional Assessment Short Form (33%, n=4). Inflammation was the most frequent etiological criterion (92%, n=25), followed by reduced food intake (48%, n=13) and nutrients assimilation (26%, n=7). Phenotypic criteria included weight loss (85%, n=23), low body mass index (81%, n=22) and reduced muscle mass (81%, n=22), assessed mainly by bioimpedance (52%, n=14) and arm or calf circumferences (45%, n=10). Malnutrition prevalence ranged from 14% to 78%, and severe malnutrition, assessed by 10 studies (37%), from 7% to 68%. Seven studies evaluated prognostic outcomes associated with GLIM.
Conclusion: This mapping showed wide variation in malnutrition prevalence in CKD, likely due to heterogeneity in GLIM application. Further studies are needed to support standardization.
Disclosure of Interest: None declared