PD041 - PREVALENCE OF ALTERATIONS IN BODY COMPOSITION ACCORDING TO HEART FAILURE TYPE.

PD041

PREVALENCE OF ALTERATIONS IN BODY COMPOSITION ACCORDING TO HEART FAILURE TYPE.

E. Vargas-Corona^1,2, A. Orea-Tejeda², D. González-Islas², B. Valderrábano-Salas², J. De la Borda-Paredes^2,*, L. Ramírez-Morales², D. Bonilla-Cuatepotzo², K. García-Díaz², V. Maldonado-Vargas², G. Cruz-Gijón², G. Rentería-Serralde², G. Benítez-Moya², R. Sánchez-Santillán², J. Ruan-Díaz², S. Alday-Ramirez²

¹Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México , ²Unidad Clínica de Investigación Cardiopulmonar y Metabólica, Servicio de Cardiología, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Ciudad de México, Mexico

 

Rationale: Heart failure (HF) is a syndrome characterized by structural and/or functional alterations of the heart, that
impacts the body composition, quality life and prognosis. There is no evidence about the prevalence of dynapenia, muscle wasting and respiratory sarcopenia according to HF type. Thus, our aim was to determine the prevalence of body composition alterations according to HF type (1).

Methods: A cross-sectional study, 487 patients >18 years with HF were included. Classified as: HF preserved (HFpEF), HF mildly range (HFmrEF) and HF reduced (HFrEF). Patients hospitalized < 3 months were excluded. Body composition was evaluated by bioelectrical impedance, dynapenia, muscle wasting and sarcopenia was defined according to EWGSOP2 guides. Group differences were analyzed using X2 for qualitative variables and ANOVA for quantitative variables.

Results: Among the 487 patients, 57.9% were men with mean age of 63.75 ± 14.41 years; 59.42% had hypertension and
43.6% diabetes. The patients with HFpEF had higher body mass index (30.11 ± 7.52 vs 27.32 ± 6.96 and 25.86 ± 5.07, p<0.001, respectively) compared to HFmrEF and HFrEF.

In relation to body composition, 81.25% had abdominal obesity and 44.9% dynapenia; in subjects with HFmrEF a higher respiratory sarcopenia was found (25% vs. 5.21% and 12.5%, p=0.046, respectively) respect to HFpEF and HFrEF.

 

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Conclusion: In HF a high prevalence of abdominal obesity and dynapenia was found, as well as a higher prevalence of respiratory sarcopenia in patients with HFmrEF, which increases the risk of cardiovascular and worse prognosis (2).

References: 1. Fu K, et al. The role of body composition in left ventricular remodeling, reverse remodeling, and clinical outcomes for heart failure with mildly reduced ejection fraction: more knowledge to the “obesity paradox.” Cardiovascular Diabetology. 2024 Sep 11;23(1):334.

2. Zhang Y, et al. Sarcopenia in Heart Failure. ESC Heart Failure. 2021 Apr 1;8(2):1007–17.

 

Disclosure of Interest: None declared