P409 - EFFECTIVENESS OF NUTRITION SUPPORT TEAMS IN PREVENTING CENTRAL LINE-ASSOCIATED BLOODSTREAM INFECTIONS DURING THE COVID-19 PANDEMIC

P409

EFFECTIVENESS OF NUTRITION SUPPORT TEAMS IN PREVENTING CENTRAL LINE-ASSOCIATED BLOODSTREAM INFECTIONS DURING THE COVID-19 PANDEMIC

H. Maki^1,*, A. Futamura², T. Koseki³, J. ida⁴, A. Suzuki⁵, N. Muroi⁶, M. Myotoku⁷, K. Mizutani⁸, H. Ogino⁹, Y. Taniguchi¹⁰, K. Higashi¹¹, M. Usui¹²

¹Department of Pharmacy, Kofu city regional medical center, Kofu, ²Department of Pharmacy, Fujita Health University Nanakuri Memorial Hospital,, Tsu, ³Department of Pharmacotherapeutics and Informatics, Fujita Health University School of Medicine, Toyoake, ⁴Hospitalization Support Center, Saiseikai Yokohama-shi Nanbu Hospital, Yokohama, ⁵Department of Pharmaceutical Sciences, School of Pharmaceutical Sciences, Kyushu University of Medical Science, Nobeoka, ⁶Department of Pharmacy, Kobe City Medical Center General Hospital, Kobe, ⁷Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, ⁸Department of Pharmacy, Toya Onsen Hospital, Toyakocho, ⁹Tokai Pharmacy, Tokai Pharmacy in front of Nakatsugawa Municipal Hospital, Nakatsugawa, ¹⁰Department of Pharmacy, Inabe General Hospital, Inabe, ¹¹Department of Pharmacy, Asanogawa general hospital, Kanazawa, ¹²Department of Surgery & Palliative Medicine, Fujita Health University School of Medicine, Toyoake, Japan

Rationale: Central line-associated bloodstream infections (CLABSI) significantly increase morbidity and mortality in hospitalized patients. This study aims to investigate whether nutrition support teams (NST) effectively prevent CLABSI during the COVID-19 pandemic.

Methods: We retrospectively analyzed the incidence of CLABSI as well as the presence or absence of additional medical fees for NST activity between 2019 and 2021, including the period before and after the COVID-19 pandemic. Subsequently, we performed between-group comparisons of the CLABSI incidence. CLABSI rates were compared based on cumulative per 1000 catheter uses during the relevant period.

Results: Among 47 facilities that were registered for participation, there were 34 and 13 facilities with and without additional medical fees for NST activity (NST and non-NST groups, respectively). The CLABSI incidence rate was significantly lower in the NST group 0.96 [0.28–1.73] than in the non-NST group 1.25 [075–6.10] (p < 0.05). Before the pandemic, the NST group had a lower CLABSI rate per 1000 catheter uses than the non-NST group 2019: 0.70 [0.12–1.26] vs 2.10 [0.62–5.97]. During the pandemic, the CLABSI incidence showed no significant between-group difference 2020: 0.99 [0.51–1.61] vs 1.01 [0.80–4.16]; 2021: 1.24 [0.44–2.35] vs 1.96 [1.23–5.31]; however, the CLABSI rates in the NST group remained low.

Conclusion: NST facilities demonstrated lower CLABSI incidence compared to non-NST facilities throughout the study period, indicating NST effectiveness in CLABSI prevention during the COVID-19 pandemic.

Disclosure of Interest: None declared