P031 - MALNUTRITION IN PATIENTS TREATED FOR LARYNGEAL CANCER: STUDY OF SEVERITY FACTORS

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P031

MALNUTRITION IN PATIENTS TREATED FOR LARYNGEAL CANCER: STUDY OF SEVERITY FACTORS

R. Laraichi1,2,*, S. Smiti1,2, F. Z. Chraa1,2, K. Nouni1,2, A. Lachgar1,2, H. El kacemi1,2, T. kebdani1,2, K. Hassouni1,2

1radiotherapy, national institute of oncology, 2Faculty of medecine, Mohammed V university, Rabat, Morocco

 

Rationale: Malnutrition is very common in patients treated for laryngeal cancer. Loss of appetite, difficulties related to dysphagia or pain, changes in taste, food aversions, and radiation-induced mucositis are significantly associated with rapid weight loss.

This work aims to research the severity factors of malnutrition in patients treated for laryngeal cancer, to identify the profile of patients at risk who should benefit from specific nutritional support.

Methods: Retrospective study conducted in the radiotherapy department at the National Institute of Oncology in Rabat, including patients followed for laryngeal cancer treated with adjuvant or exclusive curative radiotherapy during the study period from January 2024 to December 2024. Epidemiological, clinical and therapeutic data of patients were collected retrospectively from the ENOVA database. 

Results: Among the 53 patients treated for laryngeal cancer by radiotherapy during the study period, 53% were malnourished before radiotherapy and 73.5% at the end of irradiation. Analysis of epidemiological, clinical and therapeutic factors revealed some aggravating factors: age > 65 years (p=0.04), supraglottic location and panglottic tumors (p=0.05), locally advanced stage (p=0.05), dysphagia (p<0.05), social isolation (p=0.1), socioeconomic level (p=0.1), unceived smoking (p=0.05), chemotherapy associated with radiotherapy (p=0.05), grade of mucositis (p=0.05) and intercurrent diseases (p=0.1).

41% of malnourished patients were hospitalized during radiotherapy for parenteral nutrition and nutritional dietary monitoring, while 25% required enteral nutrition via gastrostomy or jejunostomy feeding. 

Conclusion: Malnutrition must be monitored early and be the subject of rigorous dietary monitoring in patients treated for laryngeal cancer, particularly in the presence of severity factors.

Disclosure of Interest: None declared