PP171 - PROGNOSTIC VALUE OF SARCOPENIA ASSESSED USING BODY MASS INDEX (BMI)-ADJUSTED CALF CIRCUMFERENCE (CC) IN HOSPITALIZED PATIENTS WITH EXCESS BODY WEIGHT

PP171

PROGNOSTIC VALUE OF SARCOPENIA ASSESSED USING BODY MASS INDEX (BMI)-ADJUSTED CALF CIRCUMFERENCE (CC) IN HOSPITALIZED PATIENTS WITH EXCESS BODY WEIGHT

V. S. Chites^1,*, J. A. D. M. Costa², G. B. D. A. E. Silva³, A. K. Ramos⁴, F. M. Silva⁵, J. C. de Almeida^6,7

¹Medical Sciences Graduate Program in Endocrinology, ²Nutrition Food and Health Graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, ³Multiprofessional Residency Program in Family Health, Universidade Federal de Santa Catarina, Araranguá, ⁴Multiprofessional Health Residency Program in Oncology and Palliative Care, Hospital de Clínicas de Porto Alegre, ⁵Nutrition Department, Nutrition Sciences Graduate Program, Health Sciences Graduate Program, Universidade Federal de Ciências da Saúde de Porto Alegre, ⁶Nutrition Department, Universidade Federal do Rio Grande do Sul, ⁷Nutrition and Dietetic Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil

Rationale: Sarcopenia is characterized by the loss of muscle mass (MM) and function, but assessing MM is challenging in patients with excess body weight. This study evaluates the prognostic value of sarcopenia assessed using BMI-adjusted CC in hospitalized patients with excess body weight.

Methods: Prospective cohort with adults and older adults with excess body weight (BMI ≥25 and ≥27 kg/m², respectively) admitted to a university hospital in Brazil. SARC-F, handgrip strength (HGS), and CC were assessed within 72h of admission. CC was adjusted for BMI (–3, –7, and –12 cm for BMI 25–29.9, 30–39.9, and ≥40 kg/m², respectively). Reduced MM was defined as CC ≤33 cm (female) and ≤34 cm (male), and low muscle strength as HGS as <16 kg (female) and <27 kg (male). No sarcopenia was defined as SARC-F <4; probable sarcopenia as SARC-F ≥4 plus low muscle strength; and sarcopenia as SARC-F ≥4 plus low muscle strength and low BMI-adjusted CC. For analysis, probable sarcopenia and sarcopenia were grouped. Logistic regression adjusted for age-adjusted Charlson Comorbidity Index (aCCI) examined associations with prolonged length of stay (≥7 days), readmission, and six-month mortality.

Results: Among 473 patients (56 ± 14 years; 52.4% female; BMI 31.7 ± 4.4 kg/m²), 23% had cancer and 85% were surgical patients. The median aCCI was 2 (interquartile range 1–4). The prevalence of probable sarcopenia or sarcopenia was 12.5% and was independently associated with prolonged length of stay (odds ratio 1.86, 95% confidence interval 1.04-3.35). No association was observed with readmission or mortality.

Conclusion: Probable sarcopenia or sarcopenia, assessed using BMI-adjusted CC to estimate muscle mass, was independently associated with prolonged hospital stay in patients with excess body weight, highlighting the potential clinical relevance of this approach in this population.

Disclosure of Interest: None declared