PD024 - ENTERAL AND PARENTERAL NUTRITION IN CLINICAL PRACTICE:EVALUATION OF REAL-WORLD DATA ACCORDING TO RENAL FUNCTION

PD024

ENTERAL AND PARENTERAL NUTRITION IN CLINICAL PRACTICE:EVALUATION OF REAL-WORLD DATA ACCORDING TO RENAL FUNCTION

I. KURAN^1,*, C. KAYABAŞI¹, Y. N. DOĞANCI², S. ATADz, F. TAMER², N. ERTEN², P. ONAR², B. KELLECİ ÇAKIR³, M. EŞME¹, S. K. DEMİRKAN³, M. G. HALİL¹

¹İç Hastalıkları Anabilim Dalı, Geriatri Bilim Dalı, ²Klinik Beslenme Anabilim Dalı, Hacettepe Üniversitesi Tıp Fakültesi, ³Klinik Eczacılık Anabilim Dalı, Hacettepe Üniversitesi Eczacılık Fakültesi, Ankara, Türkiye

Rationale: Since data on the effect of renal function on nutrition are limited,we aimed to evaluate nutritional routes and energy-protein delivery per kilogram (kg) according to glomerular filtration rate(GFR).

Methods: A total of 425 patients were included in 2025 after excluding those receiving renal replacement therapy [GFR≥60 mL/min/1.73m² (n=336), 30–59 (n=63), <30 (n=26)]. Clinical characteristics,Nutritional Risk Score-2002(NRS-2002),nutritional routes,and energy-protein delivery per kg were recorded (Figure1). Chi-square and Kruskal–Wallis tests were used,and p<0.05 was considered statistically significant.

Results: The median age was 65(52–75);as GFR decreased,age(p<0.001) and NRS-2002(p=0.004) increased significantly.The distribution of nutritional modalities[enteral(n=130, 30.6%); parenteral(n=278, 65.4%);combined enteral and parenteral (n=17,4%)] was similar across GFR groups(p=0.573). Nutritional routes[enteral: nasogastric (NG) / percutaneous endoscopic gastrostomy (PEG) / others (p=0.156) and parenteral: peripheral/central (p=0.261)] were similar.In enteral,parenteral,and combined enteral and parenteral nutrition,median calorie values were 25(16–30), 17(12.7–21.5),and 34(28.9–51.2) kcal/kg/day,respectively;protein values were 1.2(0.77–1.5), 0.8(0.6–1.0),and 1.9(1.25–2.5) g/kg/day,respectively,with no differences between groups(all p>0.05).Across groups,calorie and protein were similar in parenteral routes(p=0.244; p=0.450).In enteral routes,calorie was similar(p=0.371),while protein administered via NG decreased as GFR decreased(1.3; 0.75; 0.7 g/kg/day; p=0.047);protein was similar in PEG/other routes(p>0.05).

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Conclusion: In practice,nutritional therapy is largely applied similarly according to renal function and is individualized to a limited extent.The reduction in protein administered via NG suggests more cautious nutritional practices in patients with advanced renal disease.

Disclosure of Interest: None declared