LB129 - EFFECTIVENESS OF A MULTIMODAL PREHABILITATION PROGRAM IN ONCOLOGIC PATIENTS UNDERGOING SURGERY

LB129

EFFECTIVENESS OF A MULTIMODAL PREHABILITATION PROGRAM IN ONCOLOGIC PATIENTS UNDERGOING SURGERY

C. Díaz Gómez^1,*, J. I. Argüelles Antuña¹, M. Martín Cuadrado¹, J. Rengel Jimenez¹, L. López Amor¹, B. García Arias¹, L. Álvarez García¹, A. L. Balán Mariño¹, T. Savlik¹, S. Villalgordo García¹, M. Valledor Méndez¹

¹Intensive Care, Hospital Universitario San Agustín, Avilés, Spain

Rationale: Multimodal prehabilitation in oncologic patients scheduled for major surgery aims to optimize their functional and metabolic status prior to the procedure. Nutritional support is a cornerstone of this strategy, essential for enhancing immune response, reducing postoperative complications, and promoting faster recovery. Structured interventions before surgery may be critical to patient outcomes, particularly in settings of frailty or malnutrition.

Methods: This study included oncologic patients scheduled for major surgery who underwent comprehensive preoperative assessment. Clinical history and standard biochemical parameters were collected. Nutritional and functional assessment included anthropometric measurements, body composition analysis via bioimpedance, handgrip strength testing, sarcopenia screening, and dysphagia evaluation using MECV-V and EAT-10. Functional status was assessed using the Barthel Index and mobility through the Timed Up and Go (TUG) test. The intervention included personalized dietary counseling, oral nutritional supplementation (ONS) as required, and an individualized physical activity plan.

Results: At baseline, patients showed a mean weight loss of 6.69% (SD 7.95) and a mean BMI of 27.1 kg/m² (SD 4.97). Mean phase angle was 5.03° (SD 0.85), and average handgrip strength was 24.0 kg (SD 10.8). Probable sarcopenia was present in 60 patients (42.9%), while according to GLIM criteria, 40.0% (n = 56) had moderate malnutrition and 30.0% (n = 42) had severe malnutrition. Dysphagia was detected in 12 patients (8.6%).

After the prehabilitation program and sugery, the proportion of patients with moderate malnutrition significantly decreased (from 40.0% to 24.4%). Phase angle increased by a mean of 0.61°, suggesting potential improvement in cellular health. Body composition parameters remained largely stable, despite a mean weight loss of –2.02 kg. No significant changes were observed in biochemical parameters after the prehabilitation program.

Conclusion: The implementation of a multimodal prehabilitation program in oncologic patients undergoing surgery effectively reduced the prevalence of malnutrition and helped preserve body composition and functional status in a complex clinical setting. These findings support the integration of preoperative nutritional strategies to optimize patient condition and improve postoperative outcomes.

Disclosure of Interest: None declared