P611 - FACTORS ASSOCIATED WITH ASPIRATION PNEUMONIA IN HOSPITALIZED PATIENTS RECEIVING NUTRITIONAL THERAPY

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P611

FACTORS ASSOCIATED WITH ASPIRATION PNEUMONIA IN HOSPITALIZED PATIENTS RECEIVING NUTRITIONAL THERAPY

M. Güngör1,*, Y. N. Doğancı2, F. Tamer2, N. Erten2, S. Ataç2, B. K. Çakır3, E. O. Ersoy4, M. Eşme1, C. Balcı1, K. Demirkan3, M. G. Halil1

1Department of Internal Medicine, Division of Geriatrics, Hacettepe University, 2Clinical Nutrition Unit, Hacettepe University Hospitals, Adult Hospital, 3Department of Clinical Pharmacy, Hacettepe University Faculty of Pharmacy, 4Department of Internal Medicine, Division of Intensive Care Unite, Hacettepe University, Ankara, Türkiye

 

Rationale: Aspiration pneumonia is a serious complication associated with prolonged hospitalization and increased mortality, particularly in patients receiving nutritional support (1). We aimed to identify the factors associated with aspiration pneumonia in hospitalized patients receiving nutritional therapy.

Methods: Demographic data, nutritional routes, and nutrition-related complications of 1,420 hospitalized patients were evaluated in a university hospital.

Results: Patients received either enteral (85.9%, n=1220) or enteral+parenteral nutrition (14.1%, n=200). 56 (3.9%) patients had aspiration pneumonia. Those with aspiration pneumonia were significantly older, more likely to have regurgitation and vomiting (p=0.009, p<0.01, p<0.01, respectively). Mechanical complications like tube obstruction and dislodgement appeared to be more common (p=0.031, p<0.01) in the aspiration group. The rate of patients who achieved ≥60% of their calorie targets was significantly lower in the aspiration group (p<0.001). In the logistic regression analysis, only vomiting was a statistically significant predictor (OR=7.19, 95% CI: 3.09–16.74, p<0.001).

 

Table 1: Comparison of Patients With and Without Aspiration Pneumonia

 

Variable

Aspiration Pneumonia (+)

(n=56, 3.9%)

Aspiration Pneumonia (-)

(n=1364, 96.1%)

p-value

Age (mean ± SD)

Female sex (%)

70.61 ± 20.35

48.2%

66.1 ± 18.14

44.1%

0.009

0.054

Body Mass Index (mean ± SD)

23.89 ± 7.02

23.29 ± 5.26

0.789

Dementia (%)

Stroke / Neurological disorders (%)

Cancer (%)

10.7%

12.5%

25.0%

7.3%

10.5%

42.5%

0.346

0.632

0.009

Conclusion: Older age, vomiting, regurgitation, and mechanical feeding complications were more common among patients with aspiration pneumonia. Prospective studies are needed to further explore these associations.

References: 1. Mandell LA, Niederman MS. Aspiration Pneumonia. New England Journal of Medicine. 2019;380(7):651-63.

Disclosure of Interest: None declared