P310 - AGREEMENT BETWEEN GLIM AND SGA IN ASSESSING THE NUTRITIONAL STATUS IN ONCOLOGY PATIENTS.

P310

AGREEMENT BETWEEN GLIM AND SGA IN ASSESSING THE NUTRITIONAL STATUS IN ONCOLOGY PATIENTS.

D. Miller Scheingut^1,*, M. Perelmuter¹, D. Zecharia¹, G. Borovik¹, L. Ben Haim¹, E. Haruch¹, R. Anbar¹

¹Nutrition and Dietetic Department, Tel Aviv Sourasky Medical Center , Tel aviv, Israel

Rationale: Early malnutrition assessment in oncology patients is essential. This study compared the Global Leadership Initiative on Malnutrition (GLIM) to the Subjective Global Assessment (SGA) in evaluating the nutritional status of oncology patients.

Methods: A Cross-Sectional study assessed oncology patients undergoing treatment in the oncology department, Tel Aviv Sourasky Medical Center. Nutritional status was evaluated using SGA and GLIM, with calf circumference (CC) used to assess muscle mass (Low muscle mass was defined as CC <33 cm in males and <32 cm in females). Agreement was analyzed using IBM SPSS 24.0 to calculate Cohen’s Kappa along with Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), and the Area Under the Curve (AUC) were also calculated. The chi-squared test was used to compare malnutrition severity classifications between GLIM and SGA.

Results: 216 patients (mean age 62 ± 14.46 years, 56% male); GLIM classified 69.4% as malnourished (35.6% severe), while SGA identified 59.7% (14.8% severe). The assessments showed substantial agreement (kappa = 0.689). GLIM exhibiting high sensitivity (96.1%), moderate specificity (70.1%), PPV (82.7%), NPV (92.4%), and an AUC of 0.831 (p < 0.001). GLIM detected more severe cases than SGA (χ² 52.35, p < 0.001). In males, severe malnutrition correlated with lower CC in severe vs. moderate muscle loss detected by physical exam (30.2 cm vs. 31.8 cm, p = 0.022), suggesting greater muscle loss. No significant difference was found in females (28.4 cm vs. 30.8 cm, p = 0.185).

Conclusion: GLIM and SGA showed substantial agreement, GLIM criteria exhibited higher sensitivity but moderate specificity, indicating possible overdiagnosis, especially in severe cases. CC may be less sensitive to muscle mass loss in females, requiring further research to standardize cutoff values for validating muscle mass loss severity.

Disclosure of Interest: None declared