P466 - DIETARY MANAGEMENT OF NON-DIABETIC GASTROPARESIS: A SCOPING REVIEW

P466

DIETARY MANAGEMENT OF NON-DIABETIC GASTROPARESIS: A SCOPING REVIEW

G. Fagan^1,2,*, D. E. Bear^1,2, R. Rabheru³, M. C. Lomer^1,2

¹Nutritional Sciences, King's College London, ²Nutrition and Dietetics, Guy's and St Thomas' NHS Foundation Trust, ³Nutrition and Dietetics, Imperial College Healthcare NHS Trust, London, United Kingdom

Rationale: Dietary management is key for gastroparesis. However, dietary guidelines are from studies in patients with diabetic gastroparesis, leaving uncertainty about the best dietary approaches for those with non-diabetic gastroparesis. Therefore, a scoping review of research evidence on dietary management for non-diabetic gastroparesis was performed, assessing study designs, intervention methods and their impact on symptoms, nutritional outcomes, and quality of life (QoL).

Methods: We used the Joanna Briggs Institute methodology to conduct this review. Relevant studies from 2008 were identified through a comprehensive database search. Studies were included if patients were ≥18y and had objective gastric emptying delay using scintigraphy or breath tests, related to idiopathic, autoimmune, connective tissue disorder, or post-viral causes of gastroparesis. Two researchers screened and extracted data individually and in duplicate. 

Results: A total of 6,189 studies were screened, with 88 undergoing full-text review and 15 included in final data extraction. Among these, 6 studies evaluated dietary interventions, while 9 assessed dietary intake. Of the 15 studies from which data were extracted, 3 were randomized controlled trials (RCTs) and 12 were observational. Symptom burden was assessed in 15 (100%) studies, 9 studies (60%) examined nutritional outcomes and 5 (33%) explored the impact of diet on QoL. Dietary management strategies varied widely across studies (Figure 1).

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Conclusion: Research on dietary management for non-diabetic gastroparesis has been limited, particularly RCTs. The considerable variation in dietary approaches emphasises the urgent need to establish standardised, evidence-based dietary management strategies. Well-designed dietary intervention trials are essential to clarify the impact of diet on symptoms, nutritional status, and QoL in this patient population.

Disclosure of Interest: G. Fagan Grant / Research Support from: NIHR, D. Bear Grant / Research Support from: NIHR, Other: Speaker and consulting fees from Baxter Healthcare , R. Rabheru: None declared, M. Lomer Grant / Research Support from: Crohn's and Colitis UK, GSTT Charity, Guts UK, NIHR, Other: Personal speaker fees from Janssen, Mayoly, Abbvie