PP092 - LOW BMI-ADJUSTED MID-UPPER ARM CIRCUMFERENCE, ALONE OR IN COMBINATION WITH LOW BMI-ADJUSTED CALF CIRCUMFERENCE, IS ASSOCIATED WITH ADVERSE CLINICAL OUTCOMES IN HOSPITALIZED ADULTS

PP092

LOW BMI-ADJUSTED MID-UPPER ARM CIRCUMFERENCE, ALONE OR IN COMBINATION WITH LOW BMI-ADJUSTED CALF CIRCUMFERENCE, IS ASSOCIATED WITH ADVERSE CLINICAL OUTCOMES IN HOSPITALIZED ADULTS

F. Silva^1,*, I. Knobloch¹, V. Chites², A. Kampmann¹, C. Burgel¹, J. Costa³, J. Almeida²

¹UFCSPA, ²UFRGS, Porto Alegre, ³UFPE, RECIFE, Brazil

Rationale: Given the challenges in assessing muscle mass, particularly in individuals with excess body weight, this study aimed to evaluate the association between isolated and combined low BMI-adjusted mid-upper arm circumference (MUACBMIadj) and calf circumference (CCBMIadj) and clinical outcomes in adult hospitalized patients.

Methods: Secondary analysis of two cohorts with prospectively collected data. MUAC and CC were measured using standardized protocols. BMI-adjusted values (MUACBMIadj, CCBMIadj) were calculated using sex-specific corrections. Low MUACBMIadj was defined as <28 cm (men) and <25 cm (women), and low CCBMIadj as ≤34 cm (men) and ≤33 cm (women). Outcomes included length of stay, in-hospital mortality, and six-month readmission and mortality. Analyses were performed using R Studio (version 4.4.1).

Results:  Among 925 patients [median age 58 years (IQR 46–66); 50.5% male; mean BMI 29.1 ± 5.4 kg/m²], 22.8% had low MUACBMIadj and 48.1% had low CCBMIadj, with 16.5% presenting both conditions. Low MUACBMIadj was not associated with clinical outcomes. In contrast, low CCBMIadj was associated with prolonged hospital stay (OR 1.46; 95% CI 1.09–1.95) and six-month mortality (OR 1.99; 95% CI 1.05–3.99). The combination of low MUACBMIadj and CCBMIadj was associated with higher odds of prolonged hospital stay (OR 1.64; 95% CI 1.07–2.54) and six-month mortality (OR 3.02; 95% CI 1.33–7.11).

Conclusion: Low CCBMIadj was associated with adverse clinical outcomes in hospitalized patients, with stronger associations when combined with low MUACBMIadj. These findings support the use of combined upper- and lower-limb anthropometric markers in routine clinical assessment.

Disclosure of Interest: None declared