PD1010 - PHASE ANGLE AND TEMPORAL MUSCLE THICKNESS ARE ASSOCIATED WITH NON-ROBUST STATUS IN OLDER ADULTS

PD1010

PHASE ANGLE AND TEMPORAL MUSCLE THICKNESS ARE ASSOCIATED WITH NON-ROBUST STATUS IN OLDER ADULTS

A. Temel^1,*, O. Gumuscubuk², V. Atmis², O. Ulusoy¹, E. Kavasoglu Canatan³, V. Aykac⁴, S. Demirer⁵

¹Department of Internal Medicine, ²Department of Internal Medicine, Division of Geriatric Medicine, ³Department of Clinical Nutrition and Dietetics, Ankara University Faculty of Medicine, Ankara, Türkiye, ⁴Geriatrics, Evangelisches Geriatriezentrum Berlin-Charité Universitätsmedizin, Berlin, Germany, ⁵Department of General Surgery, Ankara University Faculty of Medicine, Ankara, Türkiye

Rationale: Identifying non-robust older adults remains clinically challenging, particularly in early frailty-related decline. Phase angle (PhA), derived from bioelectrical impedance analysis, and ultrasonographically measured temporal muscle thickness are promising markers; however, their associations with non-robust status have not been sufficiently explored.

Methods: A total of 127 community-dwelling older adults (59.8% female; mean age 72.5+-5.5 years) who attending a geriatric outpatient clinic were included. Frailty was assessed using the Clinical Frailty Scale, and participants were categorized as robust or non-robust (pre-frail/frail). Spearman’s correlation, Mann–Whitney U test, multivariable logistic regression, and receiver operating characteristic (ROC) analyses were performed.

Results: PhA showed the strongest inverse correlation with CFS score (rho=−0.50, p<0.001), followed by temporal muscle thickness (TMT) (rho=−0.37, p<0.001). Compared with robust participants, non-robust individuals had significantly lower PhA and TMT values. In multivariable logistic regression analysis including both PhA and TMT, both variables remained significantly associated with non-robust status (PhA: OR 0.565, 95% CI 0.35–0.92; TMT: OR 0.568, 95% CI 0.35–0.94), whereas other muscle-related measures lost significance in multivariable models. ROC analysis showed good discrimination for PhA (AUC=0.808, 95% CI 0.704–0.912) and acceptable discrimination for TMT (AUC=0.757, 95% CI 0.633–0.881). A PhA cut-off value of ≤5.35 identified non-robust status with 90.5% sensitivity and 62.3% specificity.

Conclusion: PhA and TMT were associated with non-robust status and may be useful as practical markers in frailty-oriented assessment of older adults.

Disclosure of Interest: None declared