LB077 - DIGITAL INTERVENTION FOR BEHAVIOUR CHANGE AND CHRONIC DISEASE PREVENTION (DIRECTION) IN INDIVIDUALS WITH OBESITY

LB077

DIGITAL INTERVENTION FOR BEHAVIOUR CHANGE AND CHRONIC DISEASE PREVENTION (DIRECTION) IN INDIVIDUALS WITH OBESITY

C. E. Orsso¹, S. Valentine¹, T. Gormaz¹, M. Ferguson-Pell¹, S. T. Johnson², A. A. Kirkham³, D. Klein¹, N. Maeda^1,4, S. E. Neil-Sztramko^5,6, M. Quintanilha¹, B. Oladunni Salami⁷, J. F. Mota⁸, C. Prado^1,*

¹University of Alberta, ²Athabasca University, Edmonton, ³University of Toronto, Toronto, ⁴My Viva Inc, Edmonton, ⁵McMaster University, ⁶National Collaborating Centre for Methods and Tools, Hamilton, ⁷University of Calgary, Calgary, Canada, ⁸Federal University of Goiás, Goiania, Brazil

Rationale: Digital health platforms can support weight loss, but their efficacy may be enhanced by health professional-led, peer-supported online group sessions. We compared the effects of a self-guided web-based wellness platform plus online group sessions versus self-guided platform alone over 16 weeks on weight outcomes in adults with obesity.

Methods: 186 adults (40-65 y; BMI 30-<35 kg/m²) were randomized to a self-guided web-based wellness platform plus weekly 60-min group sessions (experimental, n=90) led by health professionals or to self-guided platform alone (control, n=96) for 16 weeks. All participants received a smart scale for weekly self-weighing. Outcomes were changes in weight (kg) and BMI at 8 and 16 weeks, weekly weight variability using average successive variability (ASV), and achievement of ≥5% weight loss. Between-group differences were assessed using Quade’s nonparametric analysis of covariance adjusted for baseline, and logistic regression evaluated the likelihood of ≥5% weight loss. Post hoc generalized linear mixed models compared weight between groups and over time.

Results: 158 participants completed the intervention [median (IQR) age 53 (47, 58) y; 92% female). At 16 weeks, there were no between-group differences in weight (F=2.1, P=0.15), BMI (F=1.7, P= 0.19), ASV (F=0.1, P=0.71), or likelihood of ≥5% weight loss [16% experimental, 15% control; odds ratio 1.1 (95% CI, 0.5, 2.6)]. Post hoc analysis showed weight reductions [estimated marginal means (standard error), baseline=91.1 [0.8] kg, 8-week=90.3 [0.8] kg, 16-week=89.8 (0.8) kg; P<0.01] across all participants.

Conclusion: Adding online support groups to a web-based wellness platform did not improve weight outcomes versus self-guided use. However, post hoc analysis suggests platform engagement may support modest weight reduction. Further studies should identify who benefits most and evaluate real-world effectiveness

Disclosure of Interest: C. Orsso Other: Speaker engagement and honoraria from Abbott Nutrition, scholarships from Mitacs Accelerate in partnership with My Viva Plan and KillamTrusts Award, S. Valentine: None declared, T. Gormaz: None declared, M. Ferguson-Pell: None declared, S. Johnson: None declared, A. Kirkham: None declared, D. Klein: None declared, N. Maeda Other: Postdoctoral fellow at the time of study design/initiation; currently employed by My Viva Inc, S. Neil-Sztramko: None declared, M. Quintanilha: None declared, B. Oladunni Salami: None declared, J. F. Mota: None declared, C. Prado Grant / Research Support from: Alberta Health, Consultant for: Abbott Nutrition, Nutricia, Novo Nordisk, Other: Speaker engagement with Abbott Nutrition, Nutricia, Nestle Health Science, Novo Nordisk