P663 - EFFECTS OF A MULTIMODAL DIGITAL INTERVENTION ON WAIST CIRCUMFERENCE AND BODY COMPOSITION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: FINDINGS FROM THE DIGITAL MET-REHABILITATION PILOT STUDY

P663

EFFECTS OF A MULTIMODAL DIGITAL INTERVENTION ON WAIST CIRCUMFERENCE AND BODY COMPOSITION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: FINDINGS FROM THE DIGITAL MET-REHABILITATION PILOT STUDY

B. R. da Silva^1,*, B. C. Santos¹, A. I. Radil², N. Maeda³, C. M. Prado¹, M. Ferguson-Pell⁴, D. Klein²

¹Department of Agricultural, Food & Nutritional Science, ²Department of Family Medicine, University of Alberta, ³My Viva Inc & Revive Wellness Inc, ⁴Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Canada

Rationale: Individuals with chronic obstructive pulmonary disease (COPD) have an increased risk of metabolic syndrome (MetS), which worsens health outcomes. Lifestyle interventions have shown promise in managing MetS, yet their implementation in patients with COPD remains limited. This study investigated the impact of a web-based, multimodal program on anthropometrics and body composition in patients with COPD.

Methods: This is a single-arm pilot trial integrating the Canadian Health Advanced by Nutrition and Graded Exercise (CHANGE) Program with a web-based wellness platform. Over six months, participants with stage I-II COPD and MetS engaged in self-guided digital interventions and weekly online support sessions. Assessments at baseline and 6-month included bio-electrical impedance analysis and ultrasound.

Results: Thirteen patients completed the intervention (62% males); median (IQR) age was 70 (5) years, weight 93.2 (21.4) kg, and body mass index (BMI) 32.7 (5.4) kg/m². At the end of the intervention, waist circumference (−6.1 cm, p = 0.003) and thigh muscle thickness (−0.7 cm, p = 0.045) both decreased significantly. Trends were observed for reductions in weight (−3.7 kg, p = 0.064), BMI (−1.6 kg/m², p = 0.079), and subcutaneous adipose tissue thickness (−0.4 cm, p = 0.084). Change in fat-free mass (FFM) was inversely associated with baseline % fat mass (FM) (r = −0.683, p = 0.021) and BMI (r = −0.682, p = 0.021).

Conclusion: This pilot intervention led to reductions in waist circumference, with trends toward reduction of adiposity. Lower BMI and FM percentage were associated with more pronounced gains in FFM. Funding: University Hospital foundation; Mitacs

Disclosure of Interest: B. da Silva: None declared, B. Santos: None declared, A. Radil: None declared, N. Maeda Other: Became an employee of My Viva Plan during the course of the study, C. Prado Consultant for: Abbott Nutrition, Nutricia, Novo Nordisk, Other: Speaker engagement: Abbott Nutrition, Nutricia, Nestle Health Science, Novo Nordisk, M. Ferguson-Pell: None declared, D. Klein: None declared