LB094 - BEYOND WEIGHT LOSS: EVALUATING THE EFFECTIVENESS OF BARIATRIC PREHABILITATION WITH COMBINED LOW CALORIE DIET AND EXERCISE ON BODY COMPOSITION AND GLYCEMIC CONTROL

LB094

BEYOND WEIGHT LOSS: EVALUATING THE EFFECTIVENESS OF BARIATRIC PREHABILITATION WITH COMBINED LOW CALORIE DIET AND EXERCISE ON BODY COMPOSITION AND GLYCEMIC CONTROL

R. M. Shariff^1,* on behalf of Mohammad Shukri Jahit

¹Surgery, National Cancer Institute, Putrajaya, Malaysia

Rationale: Preoperative prehabilitation prior to major surgery enhances physical and nutritional readiness in anticipation of surgical stress. Bariatric surgery frequently results in muscle loss as part of weight reduction efforts. This study evaluated the preservation of muscle mass and the metabolic effects of glycemic control through the combination of a low-calorie diet and intensive exercise regimen before bariatric surgery.

Methods: This prospective interventional cohort study involved 44 patients with class II and III obesity (82.1% female; mean age 40.4±7.72 years; mean BMI 43.5±15.61 kg/m²), including 52.2% with diabetes mellitus. Participants underwent a two-week regimen incorporating low calorie diet protocol along with supervised aerobic and resistance training. Parameters obtained from bioelectrical impedance analysis and glycaemic markers were evaluated both before and after the intervention.

Results: After the 2-week intervention, patients exhibited a weight reduction of 4.3% (116.1±21.18kg to 105.4±24.14kg, p=0.010) while maintaining skeletal muscle mass (SMI: 8.2±1.08kg/m² to 8.3±1.10kg/m², p<0.001). Phase angle improved (5.2°±0.57 to 5.6°±0.58, p<0.001), total fat mass decreased by 3.5% (p<0.036), and extracellular water ratio was reduced (p=0.003). Metabolic indicators showed improvement with lower fasting blood glucose levels (6.6±2.10mmol/L to 5.5±1.31mmol/L, p=0.001). Among diabetic participants, 78% achieved complete remission and 22% partial remission. Visceral adiposity reduced by 7.4%, though this change was not statistically significant (238.6±32.61 to 220.9±63.18, p=0.063).

Conclusion: A concise 2-week preoperative intervention that integrates low calorie diet with supervised exercise effectively enhances body composition while maintaining lean muscle mass and significantly improves glycaemic control in candidates for bariatric surgery. This strategy holds promise for enhancing surgical outcomes by improving preoperative metabolic status.

References: Carli, F., Scheede-Bergdahl, C., & Awasthi, R. (2021). Prehabilitation in bariatric surgery: A systematic review and meta-analysis of randomized controlled trials. Surgery for Obesity and Related Diseases, 17(8), 1482-1492.Gonzalez-Correa, C. H., Castano-

Gonzalez, J. C., & Martinez-Sanchez, L. M. (2020). Bioelectrical impedance analysis for body composition assessment in bariatric surgery patients: A validation study. Clinical Nutrition, 39(12), 3695-3703.

Disclosure of Interest: None declared