LB008 - SCREENING OF SARCOPENIA STATUS IN PATIENTS ADMITTED TO THE MEDICAL ONCOLOGY OUTPATIENT CLINIC

LB008

SCREENING OF SARCOPENIA STATUS IN PATIENTS ADMITTED TO THE MEDICAL ONCOLOGY OUTPATIENT CLINIC

 

E. Toruk^1,*, G. Akbulut², O. Yazıcı³

¹Medical Faculty Hospital, Clinical Nutrition Unit, Gazi University, Ankara, ²Faculty of Health Sciences, Department of Nutrition and Dietetics, Kent University, İstanbul, ³Faculty of Medicine, Internal Medicine, Oncology , Gazi University, Ankara, Türkiye

 

Rationale: Sarcopenia is a common complication in cancer patients that negatively affects quality of life. This study aims to evaluate the prevalence of sarcopenia, malnutrition, and related factors in solid cancer patients aged between 18 and 64 years who are newly diagnosed and attending the Medical Oncology Clinic for the first time.

Methods: Cross-sectional study

132 patients (68 females, 64 males).

Nutritional assessment: PG-SGA SF and GLIM criteria.

Sarcopenia assessment: BIA, handgrip strength, gait speed.

Physical activity assessment: IPAQ-SF.

Phase angle measurement and muscle function evaluation were performed

Results: The most common cancer types in the patient group were gastrointestinal, breast and lung cancers.

Result 1: Malnutrition prevalence: PG-SGA SF: 57.6% , GLIM: 50%

Result 2: Physical inactivity increases the risk of severe sarcopenia by 13 times.

Result 3: Low phase angle is significantly associated with sarcopenia and severe sarcopenia.

Phase Angle Mean Values

Group                 Mean Phase Angle (°)

Normal                          5.8 ± 1.1

Possible Sarcopenia      4.6 ± 0.9

Sarcopenia                       3.8 ± 0.7

Severe Sarcopenia         3.2 ± 0.6

Conclusion: The prevalence of sarcopenia and malnutrition is high in newly diagnosed non-elderly cancer patients presenting to medical oncology clinics. Early diagnosis and timely intervention of nutritional deterioration have the potential to positively impact the treatment process. Regular monitoring of nutritional status and body composition is recommended in clinical practice. Phase angle should be taken into account in sarcopenia screening. Combining nutritional support with personalized physical activity planning may help preserve muscle mass and function.

References: Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age and Ageing. 2019;48(1):16-31.

Arends J, Bachmann P, Baracos V, et al. ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition. 2017;36(1):11-48.

Jensen GL, Cederholm T, Correia MITD, et al. GLIM criteria for the diagnosis of malnutrition: A consensus report. Clinical Nutrition. 2019;38(1):1-9.

Norman K, Stobäus N, Gonzalez MC, et al. Hand grip strength: outcome predictor and marker of nutritional status. Clinical Nutrition. 2011;30(2):135-142.

Guo Y, Shi H, Yu Z, et al. Association of low phase angle with sarcopenia and frailty in hospitalized cancer patients. Journal of Cachexia, Sarcopenia and Muscle. 2020;11(6):1302-1310.

Disclosure of Interest: None declared