P925 - EVALUATION OF THE DEPRESSION AND ANXIETY LEVELS IN PATIENTS RECEIVING PARENTERAL NUTRITION

P925

EVALUATION OF THE DEPRESSION AND ANXIETY LEVELS IN PATIENTS RECEIVING PARENTERAL NUTRITION

B. Yakut^1,*, N. Yalçın¹, B. Kelleci Çakır¹, S. Ataç², F. Tamer², K. Demirkan¹, M. Halil³

¹Department of Clinical Pharmacy, Hacettepe University Faculty of Pharmacy, ²Clinical Nutrition Unit, Hacettepe University Hospitals, Adult Hospital, ³Department of Internal Medicine Division of Geriatrics, Hacettepe University Faculty of Medicine, Ankara, Türkiye

Rationale: Parenteral nutrition (PN) therapy has been associated with quality of life and psychosocial well-being. This study aimed to evaluate the emotional state of adult inpatients receiving PN.

Methods: This prospective observational study was conducted at a tertiary university hospital. Demographic data, length of stay (LOS) and the use of psychotropic drugs were recorded. Anxiety and depression levels were evaluated with the Hospital Anxiety and Depression Scale (HADS, 0-21 points). Patients’ distress levels and problem lists were assessed with the National Comprehensive Cancer Network’s Distress Thermometer (NCCN, 0-10 points). Local ethics committee approved.

Results: A total of 32 patients enrolled and 18 patients were included in the study (55.6% female; median [IQR] age: 59.5 [20.25] years; BMI: 20.6 [6.12] kg/m²; LOS: 29 [40] days; NRS-2002: 4 [1]). Of the patients, 13 were from oncology wards. Patients reached the calorie targets on a median of day 5 of PN. Peripheral PN was administered to 11 patients. Polypharmacy (≥5 medications) was present in 14 (77.8%) patients and 3 (16.7%) patients were using at least one psychotropic drug. According to HADS, 14 (77.8%) patients had moderate to severe depressive symptoms, while 9 patients (50%) had moderate to severe anxiety. The median subjective distress level was 3 (5.2). The most frequent physical problems were fatigue (94.4%) and nausea (83%). A strong and statistically significant positive correlation was observed between anxiety scores and distress levels (r=0.931, p <0.001). Patients using at least one psychotropic drug had significantly higher distress scores (p=0.039).

Conclusion: This study demonstrates a high prevalence of anxiety and depression in hospitalized patients receiving PN. The significant correlation between anxiety and distress levels emphasizes the need for routine psychological assessment.

Disclosure of Interest: None declared