P329 - NUTRITIONAL STATUS AND WEIGHT LOSS AFTER CYSTECTOMY – A PROSPECTIVE OBSERVATIONAL STUDY

P329

NUTRITIONAL STATUS AND WEIGHT LOSS AFTER CYSTECTOMY – A PROSPECTIVE OBSERVATIONAL STUDY

J. H. Hundebøll^1,*, A. F. Olesen¹, I. Wessel^1,2, A. M. Poulsen³, A. Rytter¹

¹Department of Transplantation and Digestive Diseases, Rigshospitalet, Clinical Nutrition Center, ²Department of Clinical Medicine, Copenhagen University, ³Department of Urology, Rigshospitalet, Copenhagen, Denmark

Rationale: Limited data describe the extent of nutritional challenges faced by patients following cystectomy. This study aimed to quantify postoperative nutritional intake and weight trajectories and to identify key factors limiting oral intake in this patient group.

Methods: Over a four-month period, 25 consecutive patients undergoing cystectomy at Rigshospitalet, a tertiary referral hospital in Denmark, were enrolled in a prospective observational study. Data were collected daily from postoperative day (POD) 1 to 7 and on POD 14 and 30. Nutritional intake was assessed through food diaries (POD 1–7) and dietary recall (POD 14 and 30), with daily calculations of energy- and protein coverage. Additional parameters included weight development, bowel function, medication use, and nutritional impact symptoms (NIS). All patients received the department’s standard nutritional care, including support from designated, proactive clinical dietitians.

Results: Impaired bowel function (68%) and lack of appetite (76%) were the most frequently reported NIS during POD 1–7. During hospitalization patients achieved an average of 39% (SD 18) of their energy needs and 37% (SD 21) of protein needs; no patients achieved adequate nutrition. By POD 30, 25% of patients had reached sufficient coverage. No significant weight change was observed from POD 1–7. However, substantial weight loss was evident by POD 14 (p < 0.001) and continued through POD 30 (p < 0.001). Gastric decompression tubes were placed in 40% of patients, and this subgroup experienced the highest median weight loss by POD 30 (p = 0.025), with a median reduction of 7.1% (IQR: 5.9%–7.9%) of bodyweight.

Conclusion: Despite targeted oral nutritional therapy, patients had low postoperative energy and protein intake and experienced significant weight loss. Oral intake was limited by impaired bowel function, which was particularly pronounced in patients with gastric decompression tubes.

Disclosure of Interest: None declared