PD783 - TO WHAT EXTENT ARE HIGH ADHERENCE TO A MEDITERRANEAN DIET (MEDILITE SCORE >10) AND SUFFICIENT PHYSICAL ACTIVITY LEVELS (IPAQ >600 MET-MIN/WEEK) ASSOCIATED WITH LOWER ADIPOSITY AND IMPROVED QUALITY OF LIFE (QOL) AMONG BREAST CANCER SURVIVORS?
PD783
TO WHAT EXTENT ARE HIGH ADHERENCE TO A MEDITERRANEAN DIET (MEDILITE SCORE >10) AND SUFFICIENT PHYSICAL ACTIVITY LEVELS (IPAQ >600 MET-MIN/WEEK) ASSOCIATED WITH LOWER ADIPOSITY AND IMPROVED QUALITY OF LIFE (QOL) AMONG BREAST CANCER SURVIVORS?
A. Ruaro1,*, F. Busin2, M. Baldo3, V. Mosele3, F. Bonamonte3, V. Tronca3, R. Giaretta3, R. De Vivo4, L. Borgato4, M. Padovani5, Z. Baretta5, F. Bassan6, C. Santini6
1Curare a Casa ODV, 2Raggio di Sole ODV, 3Amici del Quinto Piano, 4Oncology, San Bortolo General Hospital, Vicenza, 5Oncology, Vittorio Emanuele II General Hospital, Montecchio Maggiore (VI), 6Oncology, Alto Vicentino General Hospital, Santorso (VI), Italy
Rationale: Scientific literature increasingly classifies Nutrition and Physical Activity as Integrated Oncology Therapy. For breast cancer patients on hormone therapy, this approach is essential to counteract treatment-related toxicity. The SeTA service in Vicenza has developed a structured, clinically validated counseling program focused on these aspects
Methods: Between 2023 and 2025, 304 follow-up breast cancer patients were evaluated at baseline. High nutritional Mediterranean diet compliance was defined as MD >10; physical activity was assessed via IPAQ Questionnaire, targeting a threshold of >600 MET-min/week; body composition and adiposity were evaluated through Body Mass Index (BMI), Waist Circumference (WC, cm), and Fat Mass percentage (%FM). Finally, Quality of Life (QoL) was measured using a 4-point self-assessment scale ranging from poor to excellent.
Results: Patients meeting both the MD score>10 and IPAQ >600 criteria typically exhibit a better body composition with: lower BMI (ΔBMI = -1,6 kg/m2: 26,2 vs 27,8 kg/m2, p<0,0001), lower waist circumference (WC) (ΔWC = -5,2: 84,7 vs 90,0 cm, p < 0,0001), as well as lower fat mass (FM) (ΔFM = -2,2%: 19,6% vs 21,9%, p =0,001). A 'good/excellent' QoLo was twice as frequent in adherent vs. non-adherent patients (ΔQlo = +35%: 71.4% vs. 36.6%, p < 0.0001). There is a significant direct correlation between better lifestyle adherence and higher Qlo (OR=4,017, p=0,002) and an inverse correlation with body composition and adiposity: BMI (OR=0,876, p>0,0001), WC (OR=0,956, p<0,0001), FM (OR=0,932, p=0,001).
Conclusion: Among breast cancer patients at SeTA, those on hormone therapy with healthier habits show better quality of life and body composition, including significantly lower adiposity than less adherent peers.
Disclosure of Interest: None declared