P354 - THE ROLE OF GASTROSTOMY PLACEMENT IN PATIENT WITH LOCALLY ADVANCED LARYNX AND HYPOPHARYNX CANCER RECEIVED CHEMORADIOTHERAPY

P354

THE ROLE OF GASTROSTOMY PLACEMENT IN PATIENT WITH LOCALLY ADVANCED LARYNX AND HYPOPHARYNX CANCER RECEIVED CHEMORADIOTHERAPY

T. K. N. Nguyen^1,* on behalf of i am an author

¹Nutrition & Radiation, Oncology Hospital, Ho Chi Minh, Viet Nam

Rationale: Surveying compliance with treatment regimens in patients with locally advanced larynx and hypopharynx cancer in areas with concurrent chemoradiotherapy with or without gastrostomy placement. Evaluate complications of feeding through a gastrostomy tube and survey the patient's nutritional status during treatment.

Methods: Prospective cross-sectional study. The research population is patients with stage III-IV larynx and hypopharynx cancer who are indicated for chemoradiotherapy treated at the head and neck radiotherapy department, Oncology Hospital, Ho Chi Minh City from October 1st,  2022 to June 1st, 2023.

Results: In a study of 47 patients with locally advanced laryngeal and hypopharyngeal cancer undergoing concurrent chemotherapy, 63.9% received enteral feeding via gastrostomy, while 36.1% relied on oral intake. Treatment compliance was higher in the gastrostomy group (72%) compared to the oral feeding group (31.8%), with fewer therapy interruptions (P = 0.006). Prophylactic percutaneous endoscopic gastrostomy led to fewer skin complications (12.5%) than open surgery (64.7%, P = 0.03). After seven weeks, weight loss was greater in orally fed patients (7.4%) than in tube-fed patients (5.4%, P = 0.181).

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Conclusion: Early gastrostomy tube placement improves treatment completion in patients with advanced laryngeal and hypopharyngeal cancer undergoing chemoradiotherapy. Prophylactic percutaneous endoscopic gastrostomy is preferable to open surgery, reducing skin inflammation. Tube-fed patients experienced less weight loss than those on oral feeding, particularly in later treatment weeks.

References: Yanni A, Dequanter D, Lechien JR, et al. Malnutrition in head and neck cancer patients: Impacts and indications of a prophylactic percutaneous endoscopic gastrostomy. Eur Ann Otorhinolaryngol Head Neck Dis. 2019;136(3S):S27-S33. doi:10.1016/j.anorl.2019.01.001

Disclosure of Interest: T. K. N. Nguyen Grant / Research Support from: Learn how to research and have new informations about nutrition, Speakers Bureau of: A teacher who I has admired for a long time