P887 - EXPLORING FACTORS CONTRIBUTING TO UNINTENTIONAL WEIGHT LOSS IN HOSPITALISED PATIENTS WITH OVERWEIGHT AND OBESITY

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P887

EXPLORING FACTORS CONTRIBUTING TO UNINTENTIONAL WEIGHT LOSS IN HOSPITALISED PATIENTS WITH OVERWEIGHT AND OBESITY

N. N. Mwala1,*, E. Vasse1,2, P. Sinnige3, J. in ’t Hulst 1, M. A. de van der Schueren1,3, B. S. van der Meij 1,3

1Department of Nutrition, Dietetics and Lifestyle, HAN University of Applied Sciences , Nijmegen, 2The Nutrition & Healthcare Alliance, Ede, 3Department of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands

 

Rationale: Unintentional weight loss (UWL) is a key indicator of malnutrition. In patients with overweight/obesity, ≥5% or ≥10% UWL (GLIM criteria) may differ in impact from those with normal weight. The causes of UWL in these patients are unclear. This study explores associations between UWL and medical conditions, mealtime habits and eating behaviours of hospitalised patients with overweight/obesity. 

Methods: This cross-sectional multicentre study analysed data from 306 adult patients (≥18 years) with a BMI ≥25.0 kg/m². UWL (≥5% or ≥10% in the past year) was self-reported. Data on medical conditions, number of doctor’s visits, mealtime habits and eating behaviours were collected via questionnaire, while inflammatory markers (CRP and albumin) were retrieved from electronic records. Logistic regression models examined associations with ≥5% and ≥10% UWL.

Results: UWL was present in 22.5% (≥5%) and 12.1% (≥10%). Both levels showed positive associations with several factors but none with inflammation, meal companionship, or meal frequency.

 

Factor

UWL ≥5%

UWL ≥10%

Type 2 Diabetes

2.40 [1.24–4.63]

3.33 [1.47–7.50]

Number of Medical Conditions (0-11)

1.24 [1.03–1.51]

1.38 [1.09–1.75]

Number of Doctor’s Visits (0-6+)

1.39 [1.19–1.65]

1.49 [1.20–1.94]

Meal Skipping

2.71 [1.56–4.77]

2.57 [1.28–5.27]

Reduced Food Intake

3.32 [1.87–5.99]

2.11 [1.02–4.38]

Medical Nutrition Therapy

4.87 [2.20–10.95]

5.84 [2.41–13.83]

Healthy Diet Perception

0.50 [0.26–0.98]

0.34 [0.16–0.74]

Gastrointestinal Diseases

n.s.

2.36 [1.11–4.96]

Conclusion: UWL in hospitalised patients with overweight/obesity is positively associated with type 2 diabetes, gastrointestinal diseases, meal skipping and reduced food intake while a self-perceived healthy diet is negatively associated. These associations were comparable for ≥5% and ≥10% UWL. These findings are relevant for understanding the applicability of the GLIM criteria in patients with overweight/obesity.

Disclosure of Interest: None declared