P360 - THE ROLE OF PHYSICAL ACTIVITY IN CARBOHYDRATE METABOLISM OF CANCER PATIENTS

Linked sessions

P360

THE ROLE OF PHYSICAL ACTIVITY IN CARBOHYDRATE METABOLISM OF CANCER PATIENTS

P. S. Barcellos1,2,*, M. Lemos-Araujo3, D. M. Linhares-Sousa1, N. P. G. F. B. Borges2, D. P. M. Torres2

1DCF, UFMA, São Luís, Brazil, 2FCNAUP, Porto University, Porto, Portugal, 3DEF, UFMA, São Luís, Brazil

 

Rationale: Physical activity is the main modifiable factor of energy expenditure and a crucial component of overall health and well-being. This study aimed to evaluate the influence of physical activity on energetic compounds (VEVO2, VO2, REE kcal/min, REE kcal/hr, CHO g, CHO kcal, and METS ) measured by indirect calorimetry. 

Methods: The study was performed with 43 cancer patients (gastric cancer, cholangiocarcinoma, pancreatic cancer, liver cancer, and colorectal cancer) from Hospital São João, Portugal. Patients who practiced or did not practice physical activity regularly before hospitalization. Resting energy expenditure was measured by indirect calorimetry (Cosmed k4 b2). Statistical analysis was performed using SPSS Software and presented descriptive analysis and the Mann-Whitney U test.

Results: Table 1: Energetic compounds by indirect calorimetry in patients who did or did not physical activity before hospitalization.

Physical Activity

 

Yes

No

P-value

Total

N

24

19

 

43

VE/VO2 

55±70

47±12

0.007*

52±53

VO2 (kg)

6±8

3±1

0.002*

5±6

REE (kcal/min)

1.49±0.42

1.11±0.34

0.009*

1.32±0.43

REE (kcal/hr)

89±25

66±20

0.008*

79±25

CHO (g)

210±125

119±83

0.014*

170±116

CHO (kcal)

885±526

503±349

0.014*

716±490

METS

1.35±0.30

1.05±0.33

0.003*

1.22±0.35

 

              *P-value = 0.05 Mann-Whitnney U test

Conclusion: Physical activity before hospitalization influenced all energy compounds analyzed (VEVO2, VO2, REE kcal/min, REE kcal/h, CHO g, CHO kcal and METS), suggesting that patients who practiced physical activity regularly had greater carbohydrate needs than sedentary patients. Such metabolic changes, if not anticipated in dietary planning, may become risk factors for malnutrition since the energy balance as well as the need for macronutrients may not be adequate.

References:

References: Barcellos, P. S., M. Lemos-Araujo, D. M. L. Sousa, N. P. G. F. B. Borges and D. P. M. Torres (2024). "Factors that influence energy expenditure of cancer patients." Clinical Nutrition ESPEN 63: 995.

Disclosure of Interest: None declared