LB051 - SINGLE-CENTER STUDY OF NUTRITIONAL ADEQUACY AND TOLERABILITY OF A CONCENTRATED, PEPTIDE-BASED ENTERAL FORMULA WITH REAL FOOD INGREDIENTS

LB051

SINGLE-CENTER STUDY OF NUTRITIONAL ADEQUACY AND TOLERABILITY OF A CONCENTRATED, PEPTIDE-BASED ENTERAL FORMULA WITH REAL FOOD INGREDIENTS

C. Steel¹, L. Murch^1,*, J. Chouinard²

¹Nestle Health Science, North York, ²Bruyère Continuing Care, Ottawa, Canada

 

Rationale: There is growing interest in enteral nutrition (EN) formulas containing real food as they have familiar, recognizable ingredients and are perceived to be well tolerated. The objective of this study was to assess nutritional efficacy and tolerance of a concentrated, plant-based, peptide-based enteral formula with real food ingredients for adult patients.

 

Methods: Mixed prospective-retrospective study conducted at a complex continuing care facility in Ottawa, Canada. Participants met inclusion criteria if they were ≥18yrs old and required EN to meet ≥90% of energy needs. Study intervention included use of study formula for a minimum of 14 days (Compleat 1.5, Nestlé Health Science Canada).

Data on % formula volume received vs prescribed, presence of GI symptoms and weight change over 14 days were collected.

 

Results:         - 30 subjects (5 prospective, 25 retrospective), 60% male, mean age 62.5 yrs

        - Most prevalent diagnostic groupings were neurological/neurodegenerative (12/30, 40%) and cerebrovascular disorders/accidents (10/30, 33.3%).

        - 3% of subjects were fed via gastrostomy tube with 53% being switched to study formula for reasons of: desire for fibre +/- real food formula (31.2%), higher caloric density (31.2%) and intolerance to current formula (18.8%).

        - Subjects received a mean 93.6% (sd 23.0%) of prescribed volume from study formula.

        - No upper GI symptoms (GIS) were reported on 70.0% of patient-days. The most frequent upper GIS was high gastric residual volumes per facility protocol (72 of 410 patient-days, 17.6%). No lower GIS were reported on 77.6% of patient-days.

        - Weight was stable between baseline and end of study (73.4kg, sd 7.85 vs 74.5, sd 7.85 respectively).

Conclusion: This concentrated, plant-based, peptide-based enteral formula with real food ingredients was shown to be well tolerated and efficacious with subjects meeting 93.6% of their nutrition needs, maintaining their weight and reporting few GI symptoms during the study period.

Disclosure of Interest: C. Steel Other: Employee of Nestle Health Science Canada, L. Murch Other: Employee of Nestle Health Science Canada, J. Chouinard Grant / Research Support from: Nestle Health Science Canada