LB066 - POSSIBLE SARCOPENIA AS A RISK FACTOR FOR DELIRIUM IN OLDER PATIENTS WITH ACUTE STROKE

LB066

POSSIBLE SARCOPENIA AS A RISK FACTOR FOR DELIRIUM IN OLDER PATIENTS WITH ACUTE STROKE

A. Nagano^1,*, K. Shiozaki¹, M. Hanaoka², K. Domen³, Y. Uchiyama³, T. Koyama^3,4

¹Nursing, ²Nutrition, Nishinomiya Kyoritsu Neurosurgical Hospital, ³Rehabilitation Medicine, School of Medicine, Hyogo Medical University, ⁴Rehabilitation Medicine, Nishinomiya Kyoritsu Neurosurgical Hospital, Nishinomiya, Japan

Rationale: Delirium is a common and serious complication after stroke, but its association with sarcopenia remains underexplored in this population. We aimed to determine whether possible sarcopenia increases the risk of delirium in older patients with acute stroke.

Methods: This retrospective cohort study included 486 patients aged ≥65 years admitted to a Stroke Care Unit between April 2020 and March 2021. Possible sarcopenia was defined using grip strength and calf circumference per AWGS2019 criteria. Delirium was diagnosed using DSM-5 criteria and confirmed by a multidisciplinary dementia care team. Univariate analyses and multivariate logistic regression were used to assess the association between possible sarcopenia and delirium.

Results: Of the 486 patients, 187 (38.4%) had possible sarcopenia and 46 (9.4%) developed delirium during hospitalization. Delirium occurred more frequently in the sarcopenia group (15.0%) than in the non-sarcopenia group (6.0%) (p = 0.001). Multivariate logistic regression identified possible sarcopenia (OR: 1.98; 95% CI: 1.01–3.91; p = 0.048) and history of delirium (OR: 5.18; 95% CI: 1.51–17.80; p = 0.008) as independent predictors of delirium onset.

Conclusion: Possible sarcopenia at admission is significantly associated with an increased risk of delirium in older patients with acute stroke. Early screening for sarcopenia may enable better risk stratification and facilitate targeted prevention strategies for delirium during hospitalization.

Disclosure of Interest: None declared