PD872 - ANALYSIS OF MORPHOFUNCTIONAL ASSESSMENT IN COLORECTAL CANCER PATIENTS REFERRED TO THE NUTRITION CLINIC

PD872

ANALYSIS OF MORPHOFUNCTIONAL ASSESSMENT IN COLORECTAL CANCER PATIENTS REFERRED TO THE NUTRITION CLINIC

M. Carpio Salmerón¹, C. Marín Sospedra¹, P. Villalba Armario¹, I. Martín Pérez^1,*, A. Flores Paños¹, A. Ríos Vergara¹, M. Álvarez Martín¹, A. Pinos Blanco¹, E. Hervás Abad¹, A. Cayuela García¹, R. Cañas Angulo¹

¹Hospital General Universitario Santa Lucía, Cartagena, Spain

Rationale: To characterize the nutritional status, body composition, and functional capacity of patients with colorectal cancer (CRC) referred to the nutrition clinic, as well as to determine the prevalence of dynapenia, sarcopenia, and sarcopenic obesity, and their association with physical function.

Methods: Cross-sectional observational study in patients with CRU attended in the Nutrition clinic at Hospital General Santa Lucía (Cartagena) between August and December 2025. Anthropometric variables (BMI), nutritional diagnosis according to GLIM criteria, and body composition parameters assessed by bioelectrical impedance analysis (ASMI, body fat percentage, and phase angle) were collected.

Muscle function was evaluated using handgrip dynamometry, with dynapenia defined as values <27 kg in men and <16 kg in women (EWGSOP2 criteria). Overall functional status was assessed using the Timed Up and Go (TUG) test.

Results: A total of 40 patients were included, with a mean age of 68.8 ± 10.5 years. The mean BMI was 25.97 ± 4.36 kg/m². According to GLIM criteria, 64.1% presented disease-related malnutrition.

The prevalence of dynapenia was 45.7%, and that of sarcopenia was 14.3%. Reduced overall functional performance, assessed using the TUG test, was identified in 32.1% of patients. The mean phase angle was 5.37°, and the mean ASMI was 7.49 kg/m². Sarcopenic obesity was present in 17.5 %(10% class I, 7.5% class II).

In a subsample of 29 patients, an inverse correlation was observed between ASMI and TUG time, reaching statistical significance (p = 0.05).

Conclusion: Patients with CRC exhibit a high prevalence of malnutrition that is not adequately captured by conventional parameters. Morphofunctional assessment enables the identification of clinically relevant alterations and facilitates early intervention. Greater muscle mass was associated with better functional performance as measured by the TUG test.

Disclosure of Interest: None declared