PT09 - THE PROGNOSTIC VALUE OF PHASE ANGLE FOR OUTCOMES IN CRITICALLY ILL PATIENTS

PT09

THE PROGNOSTIC VALUE OF PHASE ANGLE FOR OUTCOMES IN CRITICALLY ILL PATIENTS

T. N. Luu^1,*, T. P. Ha¹, H. C. N. Nguyen¹, N. X. Duong²

¹Clinical Nutrition Department, Cho Ray Hospital, ²Emergency Department, American International Hospital, Ho Chi Minh, Viet Nam

Rationale: Malnutrition is a common occurrence in critically ill patients, and has been related to poor prognosis in various diseases. Using one of nutritional indices, phase angle (PhA), provided by Body Impedance Analysis (BIA) device could help predict the clinical outcome of critically ill patients to plan appropriate nutritional support for these individuals.

Methods: In a prospective cohort study among 73 patients, the nutritional biomarkers, such as serum albumin and prealbumin, and phase angle (PhA) were assessed and compared for primary endpoints, which were mortality, length of hospitalization, and length of ICU stay. Associations with ICU mortality were analyzed using univariate logistic regression. Associations between variables with length of hospital stay and ICU stay were examined separately for mortality and survival groups. Spearman correlations were used to assess associations with quantitative variables, and Mann-Whitney tests were used to assess associations with binary variables.

Results: The median patient age was 67 years (IQR: 53–80); mean APACHE II score was 22.6 ± 7.8. There was no association between phase angle and mortality in the study population and subgroup of medical ICU (MICU) patients (n = 45). However, in the surgical ICU (SICU) patients (n = 28), phase angle was independently associated with mortality (OR: 0.07; 95% CI: 0.01–0.74; p=0.027). For the outcomes of ICU length of stay and total hospital stay (LOS), phase angle showed a significant negative correlation (R = -0.352; p = 0.013 and R = -0.341; p = 0.016, respectively) in the survivor group (n = 49).

Conclusion: In this study, PhA appears to be an independent nutritional predictor of mortality in SICU patients, as well as an independent factor associated with prolonged ICU and hospital length of stay. Early assessment of PhA using BIA may help risk stratification and guide individualized nutritional strategies in critically ill patients.

Disclosure of Interest: None declared