P649 - CORRELATION BETWEEN HANDGRIP STRENGTH AND SKELETAL MUSCLE MASS IN A SWISS ADULT POPULATION

P649

CORRELATION BETWEEN HANDGRIP STRENGTH AND SKELETAL MUSCLE MASS IN A SWISS ADULT POPULATION

W. Jimaja^1,*, M. Plenc¹, Y. Dupertuis¹, S. De Breucker², C. Graf², L. Wilmart¹, V. L. Karsegard¹, L. Genton¹

¹Clinical Nutrition, ²Geriatrics, Geneva University Hospitals, Geneva, Switzerland

 

Rationale: The diagnosis of malnutrition according to the GLIM criteria include the assessment of muscle mass. When muscle mass cannot be assessed, handgrip strength (HGS) has been suggested as a proxy. This study aimed to explore the relationship between appendicular skeletal muscle mass (ASMM) and HGS in people ≥ 18 years.

Methods: Adults were recruited at an annual public event between 2021 and 2023 in Switzerland. We measured height, weight, and dominant HGS (hydraulic dynamometer, highest of 3 values). Data are shown as mean ± SD. ASMM was measured by bioelectrical impedance analysis (Geneva formula¹). Multiple linear regressions adjusted for age and fat mass percentage (%FM) were used to assess the relationship between ASMM and HGS, separately by sex.

Results: We included 695 women (44.8 ± 16.2 years, BMI 22.9 ± 3.2 kg/m², ASMM 17.2 ± 2.1 kg, %FM 28 ± 5.6 %, HGS 33.2 ± 6.5 kg) and 687 men (43.7±16.2 years, BMI 24.6 ± 2.9 kg/m², ASMM 25.9 ± 2.8 kg, %FM 19.9 ± 6.4 %, HGS 53.2 ± 9.8 kg). The multiple regression models (cf. table) show that ASMM is significantly associated with HGS in women (R² =0.38) and men (R² =0.33) and that an increase of 1 kg in ASMM added 1.41 kg of HGS in women and 1.54 kg in men.

 

 

	Women	Men
Variable	β(CI95%)	β(CI95%)
ASMM	1.41 (1.22 – 1.60)	1.54 (1.32 – 1.76)
Age	-0.11 (-0.13 – -0.08)	-0.18 (-0.21 – -0.14)
FM%	-0.25 (-0.33 – -0.19)	-0.13 (-0.22 – -0.03)

 

 

Conclusion: This study showed a positive correlation between ASMM and HGS. Age and FM% had as expected a negative impact on HGS. It supports the use of HGS as a proxy for the diagnosis of malnutrition in our population.

References: Kyle, U. G., Genton, L., Hans, D. & Pichard, C. Validation of a bioelectrical impedance analysis equation to predict appendicular skeletal muscle mass (ASMM). Clin. Nutr. 22, 537–543 (2003).

Disclosure of Interest: None declared