PP152
ASSOCIATION BETWEEN DIGASTRIC MUSCLE WASTING AND NUTRITIONAL INTAKE IN CRITICALLY ILL PATIENTS: A COHORT STUDY USING ULTRASONOGRAPHY
S. Chanpongsang1,*, R. Supannaroj2
1Internal Medicine, Phramongkutklao hospital, Bangkok, 2Internal Medicine, Roi Et hospital, Roi Et, Thailand
Rationale: Muscle wasting in critically ill patients may contribute to dysphagia through atrophy of the tongue and laryngeal muscles, including the digastric muscle. Lacking a standardized assessment, this study evaluates the association between ultrasonographic changes in digastric muscle thickness and cross-sectional area and cumulative nutritional deficiency, dysphagia incidence, and ICU outcomes.
Methods: Critically ill patients aged >20 years were included. Digastric muscle thickness and CSA were measured by ultrasonography on ICU days 0, 7, and 14, and cumulative energy and protein intake were recorded.
Results: Ninety-three eligible participants were recruited. Changes in right and left digastric muscle thickness on day 14 were -20.69% and -20.01%, respectively. On day 14, right and left digastric muscle CSA decreased by -25.55% and -24.94%, respectively. Percentage changes in muscle thickness and CSA were significantly correlated with cumulative energy deficits on days 7 and 14 (p <0.001), and with protein deficits (p <0.001).
Secondary outcomes showed significant correlations between digastric muscle atrophy on days 7 and 14 and the presence of dysphagia (p <0.001), for both thickness and CSA. Additionally, muscle atrophy was significantly associated with ICU complications and mortality.
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Conclusion: Digastric muscle wasting measured by ultrasonography was significantly associated with energy and protein deficits in critically ill patients. Furthermore, digastric muscle ultrasonography was correlated with dysphagia, aspiration and ICU outcomes, including ICU length of stay, overall hospital length of stay, and ICU mortality.
References: Chen KC, Jeng Y, Wu WT, Wang TG, Han DS, Özçakar L, et al. Nutrients. 2021;13:4043.
Jeremy DW. Curr Opin Rheumatol. 2012;24(6):623-7.
Disclosure of Interest: None declared