P981 - LAP AND WHR INDICES ARE RELEVANT PREDICTORS OF HYPERTENSION AND HIGH CARDIOVASCULAR RISK IN ADULTS AND OLDER INDIVIDUALS FROM THE SHIP-BRAZIL STUDY

P981

LAP AND WHR INDICES ARE RELEVANT PREDICTORS OF HYPERTENSION AND HIGH CARDIOVASCULAR RISK IN ADULTS AND OLDER INDIVIDUALS FROM THE SHIP-BRAZIL STUDY

R. A. M. Braga^1,*, J. G. de Souza¹, E. T. de Santa Helena², C. Valente², C. A. de Sousa², N. R. T. Damasceno¹

¹Cardiology, University of Sao Paulo, Sao Paulo, ²Public Health, University of Blumenau, Santa Catarina, Brazil

Rationale: Cardiovascular diseases remain the leading cause of global mortality, influenced by environmental and lifestyle factors. Simple indices such as visceral adiposity index (VAI), lipid accumulation product (LAP), triglyceride-glucose index (TyG), and waist-to-hip ratio (WHR) have been explored as predictors of cardiometabolic risk. This study assessed their association with hypertension and overall cardiovascular risk (CVR) in adults and older individuals from southern Brazil, aiming to identify the best predictors. 

Methods: Cross-sectional data were analyzed from 637 individuals (20–79 years) residing in Pomerode, Brazil. Hypertension was defined by self-reported diagnosis, antihypertensive use, and blood pressure measurements. CVR was estimated by ACC/AHA criteria. 

Results: The mean age was 43 years (95% CI=43.51–43.96), with 51.29% females. Most participants self-identified as white (92.63%) and preserved German culture (65.61%). Additionally, 74.23% never smoked, 33.69% reported excessive alcohol intake, and 66.53% had low to moderate physical activity. Hypertension prevalence was 29.35% (95% CI=26.26–32.65), and 20.95% (95% CI=18.71–23.37) had high CVR. All indices were associated with both conditions, but LAP and WHR were the strongest predictors. The highest LAP tertile was associated with greater hypertension prevalence (PR=2.26; 95% CI=1.66–3.07; p<0.001), while the highest WHR tertile was linked to high CVR (PR=6.53; 95% CI=4.37–9.78; p<0.001). LAP had the best discriminatory performance for hypertension (AUC=0.691), while WHR had the highest AUC for CVR (0.779). 

Conclusion: LAP and WHR emerged as the best predictors of hypertension and high CVR, reinforcing their potential as practical tools for early risk assessment and primary care.

Disclosure of Interest: None declared