P327 - EVALUATION OF NUTRITIONAL STATUS USING BIOELECTRICAL IMPEDANCE ANALYSIS IN CANCER PATIENTS RECEIVING RADIOTHERAPY: A PROSPECTIVE STUDY

P327

EVALUATION OF NUTRITIONAL STATUS USING BIOELECTRICAL IMPEDANCE ANALYSIS IN CANCER PATIENTS RECEIVING RADIOTHERAPY: A PROSPECTIVE STUDY

H. J. Kim¹, J. Y. Jang^2,*

¹Department of Radiation Oncology, Gachon University Gil Medical Center, Incheon, ²Department of Surgery , National Health Insurance Service Ilsan Hospital , Goyang, Korea, Republic Of

Rationale: Malnutrition is commonly reported to occur after radiotherapy (RT) not only in patients with head/neck or GI cancer but also in other cancer patients. Studies using bioelectrical impedance analysis (BIA) to measure body composition and malnutrition in patients treated with RT are limited. Therefore, we performed this study to examine nutritional status before and after RT in cancer patients receiving RT using BIA.

Methods: Patients who were newly diagnosed with lung, gynecological (GYN), and gastrointestinal (GI) cancer and treated with RT in a university hospital from Sep 2022 to Apr 2024 were included. BIA was measured before and after RT. The clinical information and body composition data of patients were collected prospectively.

Results: A total of 53 patients were included in the study. The mean age of the patients was 62.5 years, and 43.4% were male. Twenty-six patients (49.1%) were diagnosed with lung cancer, and 24 patients (45.3%) with GYN cancer. The SGA score before RT was A in 46 patients, B in 6, and C in 1 patient. Patients were divided into 2 groups: Group 1 with GYN and GI cancer and Group 2 with lung cancer. When comparing the BIA results before and after RT, there was a significant difference in Body weight and Obesity degree in all cohorts. Total body water(p = 0.038), Fat free mass (p = 0.038), Skeletal muscle mass (p = 0.020), and Fat free mass index (p = 0.042) were significantly decreased after RT in Group 1, while there was no difference in all BIA results before and after RT in Group 2.

Conclusion: BIA results showed that the nutritional status of GYN & GI cancer patients significantly worsened compared to lung cancer patients. A larger study on this topic is needed in the future.

References: D Unsal et al. American Journal of Clinical Oncology ; Volume 29, Number 2, April 2006

Disclosure of Interest: None declared