P602 - CONCORDANCE BETWEEN MUSCLE ULTRASOUND AND BIOELECTRICAL IMPEDANCE ANALYSIS FOR MUSCLE ASSESSMENT IN GASTRIC CANCER PATIENTS: A PROSPECTIVE STUDY

P602

CONCORDANCE BETWEEN MUSCLE ULTRASOUND AND BIOELECTRICAL IMPEDANCE ANALYSIS FOR MUSCLE ASSESSMENT IN GASTRIC CANCER PATIENTS: A PROSPECTIVE STUDY

M. Cintoni^1,^2,*, E. Rinninella^1,², M. E. Ainora³, P. C. Raoul¹, A. Strippoli⁴, C. Pozzo⁴, G. Trovato⁴, R. Graziano¹, M. Palombaro¹, G. Pulcini¹, A. Gasbarrini^2,⁵, M. C. Mele^1,², M. A. Zocco³

¹UOC Nutrizione Clinica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, ²Centro di Ricerca e Formazione in Nutrizione Umana, Università Cattolica Del Sacro Cuore, ³CEMAD, ⁴UOC Oncologia Medica, ⁵UOC di Medicina interna, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

Rationale: Muscle ultrasound (MUS) provides a non-invasive method to assess muscle quantitative and qualitative characteristics. Investigating the potential correlation between these ultrasound findings and bioelectrical impedance analysis (BIA) parameters may offer a more comprehensive evaluation of muscle status and its relation to body composition in patients affected by gastric cancer.

Methods: Patients diagnosed with gastric cancer underwent evaluation during their baseline clinical nutrition assessment. BIA and MUS evaluations were performed concurrently on this single visit day. These assessments were completed before the initiation of specific oncological treatments or tailored nutritional support.

Results: 54 patients (68.6% males, 61.4±9.2 yo mean age) were enrolled. Our findings indicate excellent concordance between muscle status parameters derived from BIA and MUS parameters. The most notable were PhA with a thickness of the right and left rectus femoris-RF (Pearson’s Coefficient 0.47 and 0.49, respectively), Skeletal Muscle Mass with a thickness of right RF (0.74) and with the cross-sectional area of RF (0.49), as well as the FFMI with the RF thickness (0.81) and with the cross-sectional area of RF (0.53).

Conclusion: MUS shows potential as a reliable tool for assessing nutritional status in patients with gastric cancer. However, larger and specifically designed future studies are required to validate these findings and correlate sonographic parameters with clinical outcomes in this population.

Disclosure of Interest: None declared