PD012 - PREDICTIVE VALUE OF GLIM VS. SGA-DEFINED MALNUTRITION FOR HOSPITAL STAY AND ALL-CAUSE MORTALITY IN ELDERLY SEPTIC PATIENTS IN THE ICU

PD012

PREDICTIVE VALUE OF GLIM VS. SGA-DEFINED MALNUTRITION FOR HOSPITAL STAY AND ALL-CAUSE MORTALITY IN ELDERLY SEPTIC PATIENTS IN THE ICU

L. Zhong^1,*

¹Department of Clinical Nutrition, Liangping District People's Hospital, Chongqing, China

Rationale: This study aimed to compare the predictive value of the recently proposed Global Leadership Initiative on Malnutrition (GLIM) criteria against the established Subjective Global Assessment (SGA) for length of hospital stay (LOS) and mortality in this population.

Methods:  A prospective cohort study was conducted involving 105 elderly (mean age 71 years, 63.8% men) septic patients admitted to our hospital ICU. Nutritional status was assessed within 48 hours of admission using both the SGA and the GLIM criteria. The primary outcomes were LOS and 28-day all-cause mortality. Multivariate Cox proportional hazards regression models were used to determine the independent association of each nutritional diagnosis with the outcomes, adjusting for key confounders including APACHE II score and comorbidities.

Results: Malnutrition prevalence was 68.6% with GLIM and 56.2% with SGA (P=0.06). Multivariate Cox models demonstrated that patients with GLIM- (HR=2.98, 95% CI 2.76-3.18) or SGA-defined (HR=2.12, 95% CI 1.80-2.31) malnutrition had a significantly higher risk of all-cause mortality compared to well-nourished patients. For hospital stay, patients identified as malnourished by GLIM or SGA had a significantly longer median LOS (both P<0.001). Furthermore, receiver-operating characteristic curve analysis showed that the GLIM criteria had a significantly higher area under the curve for predicting 28-day mortality than the SGA criteria (0.79 vs. 0.71, P<0.001).

Conclusion:  The GLIM criteria demonstrated superior predictive value for 28-day mortality compared to SGA in elderly septic ICU patients. This supports the use of GLIM for enhanced risk stratification and to guide targeted nutritional interventions.

Disclosure of Interest: None declared