P292 - DIETARY MODIFICATIONS AND CHALLENGES IN KIDNEY CANCER MANAGEMENT: INSIGHTS FROM A PATIENT SURVEY

P292

DIETARY MODIFICATIONS AND CHALLENGES IN KIDNEY CANCER MANAGEMENT: INSIGHTS FROM A PATIENT SURVEY

B. R. da Silva^1,*, C. M. Prado¹, D. Battle², N. Dizman², V. A. Master³, S. P. Psutka⁴, M. Griffith⁵, M. D. Staehler⁶

¹Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, Canada, ²KCCure, Alexandria, ³Department of Urology, Emory University, Atlanta, ⁴Department of Urology, University of Washington School of Medicine, Seattle, ⁵Anderson Cancer Center, Houston, United States, ⁶University of Munich , Muenchen, Germany

Rationale: Patients with renal cell carcinoma (RCC) often do not receive dietary guidance, even though individualized nutrition could help address their unique health challenges and improve outcomes. Understanding specific dietary challenges faced by patients is essential for developing personalized nutritional interventions that support adherence and enhance well-being

Methods: A multidisciplinary team from the Kidney Cancer Research Alliance (KCCure), including urologic surgeons, medical oncologists, dietitians and patient advocates, developed a survey to explore dietary changes and challenges among patients with RCC. The survey was broadcast between 09/2024 and 10/2024 through website, mailing lists and social media platforms. Multiple responses from the same patient were prevented using anonymized IP address tracking. Of the 1,176 participants, 492 self-identified with metastatic RCC and were receiving systemic therapy. Among them, 287 patients provided responses.

Results: Median age was 58.7 years (range 17.2–87.0). The most reported challenges included feeling overwhelmed (18.1%), difficulties in meal planning (28.7%), and limited access to appropriate foods (10.3%). Additional barriers included financial concerns (11.4%) and emotional issues (18.4%). While 55.1% reported no dietary changes, 21.6% adopted unspecified alternative diets, and smaller percentages opted for specific diets such as the Mediterranean (6.3%) and ketogenic (7%). Significant correlations were observed between dietary changes and factors like NCCN distress score, number of prescribed medications, and self-reported quality of life (p < 0.05). Challenges in maintaining dietary changes were significantly associated with male sex.

Conclusion: This study underscores the complexity of dietary decision-making in cancer care and the need for tailored nutritional interventions to improve adherence and support better health outcomes.

Disclosure of Interest: B. da Silva: None declared, C. Prado Consultant for: Abbott Nutrition, Nutricia, Novo Nordisk, Other: Speaker engagement: Abbott Nutrition, Nutricia, Nestle Health Science, Novo Nordisk, D. Battle: None declared, N. Dizman: None declared, V. Master: None declared, S. Psutka: None declared, M. Griffith: None declared, M. Staehler: None declared