P733 - EXPLORING THE RELATIONSHIP BETWEEN LIFESTYLE FACTORS AND CONTINUOUS GLUCOSE MONITORING METRICS IN PERITONEAL DIALYSIS

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P733

EXPLORING THE RELATIONSHIP BETWEEN LIFESTYLE FACTORS AND CONTINUOUS GLUCOSE MONITORING METRICS IN PERITONEAL DIALYSIS

A. Poročnik1,*, T. Simčič1, B. Knap2,3

1Department for food science, Biotechnical Faculty, 2Department of Nephrology, University Clinical Centre Ljubljana, 3Medical faculty, Universtity of Ljubljana, Ljubljana, Slovenia

 

Rationale: This study aimed to investigate the relationship between lifestyle (sleep duration, step count, and heart rate), body composition (fat-free mass index (FFMI), fat mass index (FMI) and phase angle (Pha)), and interstitial glucose measurements in peritoneal dialysis patients (PD).

Methods: A cross-sectional study was conducted at the University Medical Centre Ljubljana and included 31 participants (21 male PD patients and 10 healthy male volunteers). Lifestyle and interstitial glucose levels were monitored over 10 days. Lifestyle factors, including heart rate, step count, and sleep duration, were collected with Garmin VivoActive 4 smartwatches. Interstitial glucose levels were assessed using the Dexcom G7 continuous glucose monitoring system, with the time-in-range (TIR 3.9–10.0 mmol/L). Body composition was measured using a BIA bioimpedance device.

Results: PD patients were less physically active (6023,62±3243,87 to 8785,40±2289,92 step count; p<0,050) and had lower heart rates during activity (110,71±12,35 to 129,50±9,95bpm; p=0,02). TIR was slightly lower (95,81±5,44 to 96,60±2,32%: p=0,78), PD patients also showed lower Pha (5,59±1,07 to 6,73±0,59; p=0,013) and worse performance on the sit-to-stand test (15,57±5,16 to 27,60±2,59; p<0,001). Marginal significant differences were found in sleep duration (7,02±1,45 to 7,76±1,24 h; p=0,204), FFMI (20,41±2,28 to 18,60±2,16 kg/m2; p=0,050) and FMI (6,80±2, 77 to 6,02±1.30kg/m2; p=0.78).

Conclusion: This study highlights significant differences in lifestyle, body composition, and glucose management between PD patients and healthy individuals. PD patients exhibited lower physical activity levels, reduced exercise capacity, and poorer glucose control. Importantly, longer sleep duration in PD patients was associated with more stable glucose levels, and increased physical activity correlated with reduced glucose variability.

Disclosure of Interest: None declared