PD568 - CIRCADIAN EATING BEHAVIORS AND CARDIOMETABOLIC PROFILES IN OVERWEIGHT OR OBESE ADULTS WITH PREDIABETES: A CROSS‑SECTIONAL STUDY

PD568

CIRCADIAN EATING BEHAVIORS AND CARDIOMETABOLIC PROFILES IN OVERWEIGHT OR OBESE ADULTS WITH PREDIABETES: A CROSS‑SECTIONAL STUDY

D. Zhou^1,*, M. Ho¹, D. Y. T. FONG¹, P. H. CHAU¹

¹School of Nursing, The University of Hong Kong, Hong Kong, China

Rationale: Circadian eating and its relationship with cardiometabolic health in prediabetes remains underexplored in Asian population. This study examined the associations of eating window, meal frequency and energy distribution with cardiometabolic profiles in overweight or obese Chinese adults with prediabetes.

Methods: Baseline data from a community-based weight loss randomized controlled trial involving 199 overweight/obese adults with prediabetes were analyzed. Dietary intake was assessed via 24‑hour dietary recalls. The associations between circadian eating behaviors, particularly the eating window (≤12 vs. >12 hr/day), meal frequency (>3 vs. ≤3 meals/day), and energy distribution (morning-predominant vs. evening-predominant) with fasting glucose, 2‑hour post‑load glucose (2hrPP), glycated hemoglobin and lipid profiles were evaluated by multivariable linear regression models, with adjustment for age, sex, smoking, alcohol drinking and body mass index.

Results: Participants (68% women) had a median age of 55.2 years, body mass index (BMI) of 26.9 kg/m², and HbA1c 6.1%; 60% reported an eating window of ≤12hr, 66% consumed >3 meals/day, and 27% had a higher morning energy intake. A shorter eating window (≤12hr/day) was associated with lower total cholesterol (-0.30 mmol/L, 95% confidence interval [CI]: -0.57 to -0.04) and low‑density lipoprotein cholesterol (-0.30 mmol/L, 95% CI: -0.53 to -0.07). Higher meal frequency (>3 meals/day) was associated with lower 2hrPP (-0.52 mmol/L, 95% CI: -1.03 to -0.00). 

Conclusion: A shorter eating window was associated with favorable lipid profiles, while higher meal frequency with better glycemic control. Prospective studies are needed to determine the clinical implications of circadian eating behaviors for cardiometabolic health.

Disclosure of Interest: None declared