P715 - MEDIUM-CHAIN TRIGLYCERIDE-ENHANCED RICE IMPROVES COGNITIVE FUNCTION, ACTIVITIES OF DAILY LIVING, AND SWALLOWING ABILITY IN POST-STROKE PATIENTS WITH COGNITIVE IMPAIRMENT

P715

MEDIUM-CHAIN TRIGLYCERIDE-ENHANCED RICE IMPROVES COGNITIVE FUNCTION, ACTIVITIES OF DAILY LIVING, AND SWALLOWING ABILITY IN POST-STROKE PATIENTS WITH COGNITIVE IMPAIRMENT

S. Shimazu^1,*, Y. Yoshimura¹, H. Wakabayashi², R. Momosaki³, F. Nagano¹, A. Matsumoto¹, A. Shiraishi¹, Y. Kido¹, T. Bise¹, A. Kuzuhara¹, T. Hamada¹, K. Yoneda¹

¹Kumamoto Rehabilitation Hospital, Kumamoto, ²Tokyo Women's Medical University Hospital,, Tokyo, ³Mie University Graduate School of Medicine, Mie, Japan

Rationale: Evidence on the effects of medium-chain triglyceride (MCT) intake on cognitive function in older inpatients with cognitive impairment is limited. This study hypothesized that MCT-enhanced rice consumption would improve cognitive function, activities of daily living (ADL), and swallowing ability in this population.

Methods: A retrospective cohort study was conducted with 1,012 post-stroke inpatients, stratified by the provision of MCT-enhanced rice as part of nutritional support. Propensity score matching and multivariable regression analyses were employed to evaluate changes in cognitive function (Functional Independence Measure [FIM]-cognition), ADL (FIM-motor), and swallowing ability (Food Intake LEVEL Scale [FILS]) from admission to discharge.

Results: After applying exclusion criteria, 659 patients (mean age 76.1 years; 52.8% men) were analyzed. Following propensity score matching, patients receiving MCT-enhanced rice showed significantly greater FIM-cognition gains (median [95% CI]: 9 [5, 15] vs. 8 [5, 12], p=0.002) compared to controls. Additionally, the MCT group had higher discharge scores for FIM-motor (59 [41, 79] vs. 56 [31, 77], p=0.019) and FILS (10 [9, 10] vs. 9 [8, 10], p=0.027). Multivariable regression confirmed independent associations between MCT intake and improved outcomes for all measures.

Conclusion: MCT-enhanced rice may enhance cognitive function, ADL, and swallowing ability in post-stroke patients with cognitive impairment.

Disclosure of Interest: None declared