PD318 - NUTRITIONAL RISK FACTORS OF UNPLANNED HOSPITAL READMISSION IN ADULT CHRONIC INTESTINAL FAILURE PATIENTS DISCHARGED TO COMMUNITY

PD318

NUTRITIONAL RISK FACTORS OF UNPLANNED HOSPITAL READMISSION IN ADULT CHRONIC INTESTINAL FAILURE PATIENTS DISCHARGED TO COMMUNITY

T. Tian¹, X. Huang², Y. Zhang², Y. Li^1,*

¹Department of General Surgery, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, ²Shanghai JiaoTong University School of Medicine, Shanghai, China

Rationale: This study aimed to investigate risk factors for unplanned readmission in adults with chronic intestinal failure (CIF) on medical nutrition therapy (MNT).

Methods: Adult CIF patients discharged to community between May 2023 and December 2024 were included. Bayesian multivariable logistic regression analysis and correlation analysis were applied to assess risk factorsof unplanned readmission. Mediation analysis was used to quantify the mediation effects.

Results: Out of 217 patients, 98 (45.16%) were readmitted. Compared with the non-readmission group, the readmission group had higher fat calories (aOR: 2.502; 95% CrI: 1.258–5.405) and lower carbohydrate calories (aOR: 0.693; 95% CrI: 0.432–0.966)  derived from parenteral nutrition (PN) and exteral nutrition (EN), lower caloric intake of PN (aOR: 0.102; 95% CrI: 0.002–0.601) and lower average weekly urine output (aOR:0.030; 95% CrI: 0.002-0.391). Apart from nutritional factors, a significant correlation was revealed between outcome and serum amylase (AMS), ALT, number of surgical procedures, GGT, age, indirect bilirubin and activated partial thromboplastin time (APTT) (|r|＞0, p＜0.05). ALT mediated the association between GGT and unplanned hospital readmission with a mediating effect of 38.89%.

Conclusion: Higher caloric intake of PN may reduce readmission rates in CIF patients, while an excessive proportion of fat calories from PN and EN was associated with an increased risk of readmission.

Disclosure of Interest: None declared