LB088 - THE EFFECT OF HIGH PROTEIN NUTRITIONAL INTERVENTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AT RISK OF MALNUTRITION – PRELIMINARY DATA

LB088

THE EFFECT OF HIGH PROTEIN NUTRITIONAL INTERVENTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AT RISK OF MALNUTRITION – PRELIMINARY DATA

J. Křížová^1,2,*, Z. Kršáková^1,2

¹General University Hospital in Prague, 3rd Department of Internal Medicine, ²Charles University, 1st Faculty of Medicine, Prague, Czech Republic

Rationale: The aim of our study was to monitor and evaluate the effect of a 3-month nutritional intervention using high-protein, diabetes specific enteral nutrition in patients with type 2 diabetes mellitus (T2DM) and confirmed malnutrition. We focused on selected anthropometric parameters, muscle strength and quality of life.

Methods: Patients with T2DM who met the criteria for enteral nutrition prescription were included in the study. Selected anthropometric and laboratory nutritional and metabolic parameters, functional status, and quality of life as well as patient´s subjective feelings and compliance were assessed at baseline and after 3 months of nutritional support with high-protein diabetes specific formula. The recommended intake was two bottles of oral nutritional supplement per day (604 kcal, 40 g protein, 63 g saccharides, 21 g fat). 

Results: So far, 8 patients have been included. After 3 months, the average weight gain was 2.7 kg (range 1–4 kg), and lean body mass increased by an average of 2.5%. Improvements were observed in hand grip strength (5%) and quality of life (4%). Glycated haemoglobin and lipid parameters remained unchanged. Subjectively, patients reported improvements in quality of life (6/8), appetite (5/8), and physical performance (5/8). All patients were able to consume two bottles per day; sipping was well tolerated, and no gastrointestinal discomfort was reported.

Conclusion: A 3-month nutritional intervention with a high-protein, diabetes-specific enteral formula led to improvements in body weight, lean body mass, strength, quality of life, and appetite. The supplement was well tolerated, and no deterioration in diabetes control was observed. These are preliminary data; further participants and longer follow-up are expected.

Disclosure of Interest: J. Křížová Speaker Bureau for: Danone Nutricia, Fresenius Kabi, Z. Kršáková: None declared