P676 - IMPACT OF ENERGY INTAKE ON EXERCISE TOLERANCE IN PATIENTS WITH CARDIOVASCULAR DISEASE: A LONGITUDINAL STUDY IN A REHABILITATION HOSPITAL

P676

IMPACT OF ENERGY INTAKE ON EXERCISE TOLERANCE IN PATIENTS WITH CARDIOVASCULAR DISEASE: A LONGITUDINAL STUDY IN A REHABILITATION HOSPITAL

T. Yanase^1,^2,*, T. Matsuo¹, T. Ohtsubo^1,², H. Akaiwa^2,³, M. Kikuchi⁴, A. Shinbo¹, K. Ueno¹, S. Kozawa¹, Y. Morimoto^2,⁵

¹Nishi Memorial Port-island Rehabilitation Hospital, ²Kobe Gakuin University Graduate School, Kobe, ³Kansai Medical University Medical Center, Moriguchi, ⁴Kobe City Nishi-Kobe Medical Center, ⁵Kobe Gakuin University , Kobe, Japan

Rationale: Energy intake (EI), as a determinant of malnutrition, has been associated with exercise tolerance in patients with cardiovascular disease (CVD) in the acute hospital. In rehabilitation hospital where patients are stable condition, EI at admission (EI-a) and the amount of change in EI (ΔEI) may be related to exercise tolerance at discharge, but this is not clear.

Methods: This longitudinal study included patients with CVD transferred from acute hospitals to the rehabilitation hospital from 2020 December to 2024 September. Those with impaired ambulation, returned to acute hospital, oral intake difficulties, missing data were excluded. EI (kcal/IBW/day) at admission and discharge was calculated by the average intake of calories (7 consecutive days after admission and before discharge) adjusted for ideal body weight. The ΔEI during hospitalization was calculated by subtracting EI-a from EI at discharge. Multivariate analysis was conducted with the 6-minutes walking distance at discharge (6MWD-d) - the primary outcome of this study - as the dependent variable, adjusted for age, sex, Charlson Comorbidity Index, pre-admission Barthel Index, New York Heart Association class. An interaction term between EI-a and ΔEI was also included to assess their combined effect on 6MWD-d.

Results: A total of 87 patients (52 females, median age 78 years, median length of hospital stay 63 days) were analyzed. In multivariate analysis, EI-a was independently associated with 6MWD-d (β=5.66, p=0.043), but ΔEI (β=0.81 p=0.878) and both interaction (β=0.04 p=0.875) was not significantly associated.

Conclusion: EI-a in a rehabilitation hospital may be associated with 6MWD-d in patients with CVD. It is possible that the results of no association between ΔEI do not rule out an improvement in EI, but that the improvement may have been insufficient time to be reflected in the outcome.

Disclosure of Interest: None declared