P313 - MALNUTRITION AND OUTCOME IN HOSPITALIZED CANCER PATIENTS: A NUTRITIONDAY ANALYSYS

P313

MALNUTRITION AND OUTCOME IN HOSPITALIZED CANCER PATIENTS: A NUTRITIONDAY ANALYSYS

D. Cardenas^1,*, S. Tarantino², A. Schartmann², C. Schuh², A. Laviano³, M. Hiesmayr²

¹Nutrition Unit, Gustave Roussy, Villejuif, France, France, ²Center for Medical Data Science, Institute of Medical Statistics, Medical University of Vienna, Vienna, Austria, ³Sapienza University of Rome, Rome , Italy

Rationale: A global assessment of the prevalence of hospitalized cancer patients (CP) with or at risk of malnutrition is lacking. The nDay project collects data of hospitalized patients worldwide, allowing for investigation of the prevalence of malnutrition or its risk, as well as their impact on outcomes, in CP.

Methods: The nutritionDay (nDay) cohort 2016-2023 was analysed. Prevalence of malnutrition risk (i.e., Malnutrition Screening Tool MST>2), diagnosis of malnutrition (i.e., Global Leadership Initiative on Malnutrition GLIM criteria) and their impact on and 30-day mortality and readmission was compared between CP and nCP (non-cancer patients) using Chi-square test. Data are presented as % or mean±SD. A p<0.05 is statistical significant.

Results: when compared to nCP (n=178,729), CP (n=45,492) were more frequently at risk of malnutrition (MST>2 39.7% vs. 24.3%*), and malnourished (GLIM criteria 39.7% vs. 24.3%*). They had lower BMI (24.5 ± 5.4 vs. 25.9 ± 6.1*), ate less before admission (¼ of the meal, 14.6% vs. 9.8%*), and at nDay (¼ of the meal: 15.6% vs. 12.4%*, nothing: 14.4% vs. 11.5%*). Unintentional weight loss was more frequent than in nCP (53.1% vs. 35.9%*). In CP vs nCP, 30-day mortality [5.1% vs. 2.3%*; when MST ≥2 (6.6% vs. 2.6%*)], and 30-day readmission rates [(19.1% vs. 7.79%*), reaching 21.9% vs. 9.2% in MST ≥2 patients] were higher. *p<0.001

Conclusion: In a large cohort of hospitalized CP, the risk and the presence of malnutrition are significantly higher than in nCP, and are associated with poor outcomes. Early identification of at risk CP is mandatory to deliver immediate nutritional care.

Disclosure of Interest: D. Cardenas Speakers Bureau of: Speaker honoraria by Fresenius, Nestle, Danone; research grant by ASDIA. , S. Tarantino: None declared, A. Schartmann: None declared, C. Schuh: None declared, A. Laviano Speakers Bureau of: declares honoraria for invited lectures., M. Hiesmayr Speakers Bureau of: declares honoraria for invited lectures.