P286 - NUTRITION STATUS AND NUTRITION IMPACT SYMPTOMS AMONG ADULT PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANT IN A TERTIARY HOSPITAL

P286

NUTRITION STATUS AND NUTRITION IMPACT SYMPTOMS AMONG ADULT PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANT IN A TERTIARY HOSPITAL

A. S. Panes^1,2,*, M. C. K. S. Reyes¹

¹Internal Medicine - Medical Nutrition Section, The Medical City - Ortigas, Pasig, ²Medical Nutrition Department / Family Medicine Department, Davao Regional Medical Center, Tagum, Philippines

Rationale: Hematopoietic stem cell transplant (HSCT) procedures often result in the occurrence of nutrition impact symptoms (NIS), potentially affecting patients' nutritional status and consequently, HSCT outcomes. This study aims to determined the baseline nutritional status and NIS among adult patients undergoing HSCT in a tertiary hospital. 

Methods: A retrospective descriptive study was conducted on HSCT patients admitted to The Medical City - Ortigas from May 1, 2016, to December 31, 2022. Nutritional status was determined using the Nutrition Risk Score 2002 (NRS-2002), body mass index (BMI), and history of unintentional weight loss. 

Results: The study included 58 patients with a median age of 51 years, predominantly male. Nearly half had multiple myeloma (44.8%), and autologous HSCT was most common. Main complications were febrile neutropenia (81%) and infections (77%), with a 1.72% mortality. The median BMI was 26kg/m² (14.9 to 38 kg/m²), with 39.66% of patients classified as overweight, 37.93% as obese, and 1 patient (1.72%) as underweight. NRS-2002 scores ranged from 0 to 5, with a median of 2; 11 patients (18.97%) had high nutritional risk scores. Thirteen patients (22.41%) reported unintentional weight loss for the past six months. Common symptoms included poor appetite (94.82%), nausea (65.51%), and vomiting (48.27%), typically appearing after the conditioning regimen, with only 2 patients not experiencing any nutrition impact symptoms (NIS) throughout.

Conclusion: The results showed that most HSCT patients were overweight or obese, and the presence of high NRS-2002 scores and involuntary weight loss indicated that some were already at nutritional risk before the procedure. During the transplant, patients frequently experience NIS, which further deteriorates their nutritional status, highlighting the need for early and thorough nutritional screening.

Disclosure of Interest: None declared