P040 - EVALUATION OF SYMPTOMATOLOGY AND QUALITY OF LIFE FOLLOWING A KETOGENIC DIET DURING THE TREATMENT PERIOD OF CANCER PATIENTS MONITORED FOR GLIOBLASTOMAS

P040

EVALUATION OF SYMPTOMATOLOGY AND QUALITY OF LIFE FOLLOWING A KETOGENIC DIET DURING THE TREATMENT PERIOD OF CANCER PATIENTS MONITORED FOR GLIOBLASTOMAS

S. Smiti^1,*, R. LARAICHI¹, K. NOUNI¹, A. LACHGAR¹, H. EL KACEMI¹, T. KEBDANI¹, K. HASSOUNI¹

¹radiation therapy, national Institute of cancer, RABAT, Morocco

 

Rationale: The Glioblastoma is the most common brain tumor; and in order to reduce the symptoms of this cancer, studies have sought the impact of nutrition, particularly the ketogenic diet, on brain symptoms as well as on quality of life.

  It is wise to identify the beneficial and harmful effects of practicing this diet from a scientific perspective.

 This work aims to identify the effects of the ketogenic diet on the evolution of neurological symptoms, as well as the quality of life by worsening or improvement of cerebral symptoms on side effects.

Methods: For this, a prospective study was carried out within the radiotherapy department of the National Institute of Oncology in Rabat over a period of 3 months for the period between January 2, 2025 and March 31, 2025.

 

Results: The study involved 10 patients monitored for brain tumors during their radiotherapy treatment.

5 patients were put on a ketogenic diet versus 5 patients who kept their usual diet without carbohydrate restriction.

Our study found that 66% of patients placed on a ketogenic diet experienced an improvement in their epilepsy-like neurological symptoms during treatment compared to 48% of patients without dietary restrictions.

As for quality of life, as evidenced by a reduction in headaches, nausea, vomiting, and epileptic seizures, it improved in 55% of patients on a ketogenic diet compared to 45% of patients without dietary restrictions.

Thus, the ketogenic diet non-significantly improves cerebral symptoms and quality of life in patients (p value 0.13).

 

Conclusion: Adopting a ketogenic diet during radiotherapy treatment appears to improve patients' overall quality of life and reduce cerebral symptoms. This constantly evolving topic calls for further research to better understand the impact of this diet on the human body and tumor cells and to discover its long-term effects.

Disclosure of Interest: None declared